Entity Details

Primary name ACO12_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ8WYK0
EntryNameACO12_HUMAN
FullNameAcetyl-coenzyme A thioesterase
TaxID9606
Evidenceevidence at protein level
Length555
SequenceStatuscomplete
DateCreated2002-11-08
DateModified2021-06-02

Ontological Relatives

GenesACOT12

GO terms

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GOName
GO:0003986 acetyl-CoA hydrolase activity
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006084 acetyl-CoA metabolic process
GO:0006631 fatty acid metabolic process
GO:0006637 acyl-CoA metabolic process
GO:0008289 lipid binding
GO:0036042 long-chain fatty acyl-CoA binding
GO:0042802 identical protein binding
GO:0047617 acyl-CoA hydrolase activity
GO:0052689 carboxylic ester hydrolase activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR002913 START domainDomainDomain
IPR006683 Thioesterase domainDomainDomain
IPR023393 START-like domain superfamilyFamilyHomologous superfamily
IPR029069 HotDog domain superfamilyFamilyHomologous superfamily
IPR033120 Hotdog acyl-CoA thioesterase (ACOT)-type domainDomainDomain
IPR040170 Cytosolic acyl coenzyme A thioester hydrolaseFamilyFamily

Diseases

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