Entity Details

Primary name PGRP3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ96LB9
EntryNamePGRP3_HUMAN
FullNamePeptidoglycan recognition protein 3
TaxID9606
Evidenceevidence at protein level
Length341
SequenceStatuscomplete
DateCreated2003-11-28
DateModified2021-06-02

Ontological Relatives

GenesPGLYRP3

GO terms

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GOName
GO:0005576 extracellular region
GO:0008270 zinc ion binding
GO:0008745 N-acetylmuramoyl-L-alanine amidase activity
GO:0009253 peptidoglycan catabolic process
GO:0016019 peptidoglycan immune receptor activity
GO:0016020 membrane
GO:0016045 detection of bacterium
GO:0019730 antimicrobial humoral response
GO:0031640 killing of cells of other organism
GO:0032689 negative regulation of interferon-gamma production
GO:0032827 negative regulation of natural killer cell differentiation involved in immune response
GO:0032991 protein-containing complex
GO:0042834 peptidoglycan binding
GO:0045087 innate immune response
GO:0046982 protein heterodimerization activity
GO:0050830 defense response to Gram-positive bacterium
GO:0051701 biological process involved in interaction with host
GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002502 N-acetylmuramoyl-L-alanine amidase domainDomainDomain
IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteriaDomainDomain
IPR015510 Peptidoglycan recognition proteinFamilyFamily
IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB04736 2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOPYRANOSE(BETA1-4)-2-ACETAMIDO-1,6-ANHYDRO-3-O-[(R)-1-CARBOXYETHYL]-2-DEOXY-BETA-D-GLUCOPYRANOSE-L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELYL-D-ALANINEDrugbanksmall molecule