Entity Details

Primary name CML1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ99788
EntryNameCML1_HUMAN
FullNameChemokine-like receptor 1
TaxID9606
Evidenceevidence at protein level
Length373
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesCMKLR1

GO terms

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GOName
GO:0001501 skeletal system development
GO:0002430 complement receptor mediated signaling pathway
GO:0004875 complement receptor activity
GO:0004930 G protein-coupled receptor activity
GO:0004950 chemokine receptor activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0010759 positive regulation of macrophage chemotaxis
GO:0016021 integral component of membrane
GO:0032088 negative regulation of NF-kappaB transcription factor activity
GO:0032695 negative regulation of interleukin-12 production
GO:0038023 signaling receptor activity
GO:0045600 positive regulation of fat cell differentiation
GO:0050848 regulation of calcium-mediated signaling
GO:0120162 positive regulation of cold-induced thermogenesis

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR000826 Formyl peptide receptor-relatedFamilyFamily
IPR002258 Chemokine-like receptor 1FamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CML1_HUMANTPST1_HUMANHPRD17558413 details
CML1_HUMANTPST2_HUMANHPRD17558413 details