Entity Details

Primary name ATS3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15072
EntryNameATS3_HUMAN
FullNameA disintegrin and metalloproteinase with thrombospondin motifs 3
TaxID9606
Evidenceevidence at protein level
Length1205
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesADAMTS3

GO terms

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GOName
GO:0001701 in utero embryonic development
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0008201 heparin binding
GO:0008270 zinc ion binding
GO:0010573 vascular endothelial growth factor production
GO:0016485 protein processing
GO:0030198 extracellular matrix organization
GO:0030199 collagen fibril organization
GO:0030574 collagen catabolic process
GO:0031012 extracellular matrix
GO:0032964 collagen biosynthetic process
GO:0070062 extracellular exosome
GO:0097435 supramolecular fiber organization
GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000884 Thrombospondin type-1 (TSP1) repeatRepeatRepeat
IPR001590 Peptidase M12B, ADAM/reprolysinDomainDomain
IPR002870 Peptidase M12B, propeptideDomainDomain
IPR010294 ADAM-TS Spacer 1DomainDomain
IPR010909 PLACDomainDomain
IPR013273 ADAMTS/ADAMTS-likeFamilyFamily
IPR024079 Metallopeptidase, catalytic domain superfamilyFamilyHomologous superfamily
IPR036383 Thrombospondin type-1 (TSP1) repeat superfamilyFamilyHomologous superfamily
IPR041645 ADAM cysteine-rich domain 2DomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ATS3_HUMANUBQL2_HUMANBioGRID, IntAct32296183 details