Entity Details

Primary name TCAB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BUR4
EntryNameTCAB1_HUMAN
FullNameTelomerase Cajal body protein 1
TaxID9606
Evidenceevidence at protein level
Length548
SequenceStatuscomplete
DateCreated2006-06-27
DateModified2021-06-02

Ontological Relatives

GenesWRAP53

GO terms

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GOName
GO:0000781 chromosome, telomeric region
GO:0003723 RNA binding
GO:0005654 nucleoplasm
GO:0005697 telomerase holoenzyme complex
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0007004 telomere maintenance via telomerase
GO:0015030 Cajal body
GO:0016032 viral process
GO:0016604 nuclear body
GO:0030576 Cajal body organization
GO:0031625 ubiquitin protein ligase binding
GO:0032203 telomere formation via telomerase
GO:0034337 RNA folding
GO:0035861 site of double-strand break
GO:0042393 histone binding
GO:0042802 identical protein binding
GO:0044877 protein-containing complex binding
GO:0045739 positive regulation of DNA repair
GO:0051087 chaperone binding
GO:0051973 positive regulation of telomerase activity
GO:0070034 telomerase RNA binding
GO:0090666 scaRNA localization to Cajal body
GO:0090671 telomerase RNA localization to Cajal body
GO:1904851 positive regulation of establishment of protein localization to telomere
GO:1904867 protein localization to Cajal body
GO:1905168 positive regulation of double-strand break repair via homologous recombination
GO:2000781 positive regulation of double-strand break repair
GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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