Entity Details

Primary name CAR14_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9BXL6
EntryNameCAR14_HUMAN
FullNameCaspase recruitment domain-containing protein 14
TaxID9606
Evidenceevidence at protein level
Length1004
SequenceStatuscomplete
DateCreated2002-01-31
DateModified2021-06-02

Ontological Relatives

GenesCARD14

GO terms

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GOName
GO:0001934 positive regulation of protein phosphorylation
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006915 apoptotic process
GO:0007250 activation of NF-kappaB-inducing kinase activity
GO:0016235 aggresome
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0043066 negative regulation of apoptotic process
GO:0050700 CARD domain binding
GO:0051092 positive regulation of NF-kappaB transcription factor activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001315 CARD domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR008144 Guanylate kinase-like domainDomainDomain
IPR011029 Death-like domain superfamilyFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily

Diseases

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