Entity Details

Primary name FOXP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO15409
EntryNameFOXP2_HUMAN
FullNameForkhead box protein P2
TaxID9606
Evidenceevidence at protein level
Length715
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesFOXP2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006357 regulation of transcription by RNA polymerase II
GO:0021757 caudate nucleus development
GO:0021758 putamen development
GO:0021987 cerebral cortex development
GO:0033574 response to testosterone
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043565 sequence-specific DNA binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0050681 androgen receptor binding
GO:0098582 innate vocalization behavior

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001766 Fork head domainDomainDomain
IPR030456 Fork head domain conserved site 2SiteConserved site
IPR032354 FOXP, coiled-coil domainDomainDomain
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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