Entity Details

Primary name VISTA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H7M9
EntryNameVISTA_HUMAN
FullNameV-type immunoglobulin domain-containing suppressor of T-cell activation
TaxID9606
Evidenceevidence at protein level
Length311
SequenceStatuscomplete
DateCreated2005-03-01
DateModified2021-06-02

Ontological Relatives

GenesVSIR

GO terms

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GOName
GO:0005886 plasma membrane
GO:0010628 positive regulation of gene expression
GO:0010950 positive regulation of endopeptidase activity
GO:0016021 integral component of membrane
GO:0019899 enzyme binding
GO:0030335 positive regulation of cell migration
GO:0031638 zymogen activation
GO:0032689 negative regulation of interferon-gamma production
GO:0032693 negative regulation of interleukin-10 production
GO:0032700 negative regulation of interleukin-17 production
GO:0032720 negative regulation of tumor necrosis factor production
GO:0042802 identical protein binding
GO:0045591 positive regulation of regulatory T cell differentiation
GO:0050776 regulation of immune response
GO:0061133 endopeptidase activator activity
GO:0120158 positive regulation of collagen catabolic process
GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation
GO:2000565 negative regulation of CD8-positive, alpha-beta T cell proliferation

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR003599 Immunoglobulin subtypeDomainDomain
IPR007110 Immunoglobulin-like domainDomainDomain
IPR013106 Immunoglobulin V-set domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036179 Immunoglobulin-like domain superfamilyFamilyHomologous superfamily
IPR042473 V-type immunoglobulin domain-containing suppressor of T-cell activationFamilyFamily

Diseases

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Interactions

28 interactions

InteractorPartnerSourcesPublicationsLink
VISTA_HUMANSMAD3_HUMANBioGRID, HPRD, MINT15231748 details
VISTA_HUMANPLS1_HUMANBioGRID, HPRD, IntAct16189514 details
VISTA_HUMANS35B1_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANSMCO4_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANVAMP3_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANS35B4_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANTSN2_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANTM218_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANBMP10_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANTNFA_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANCC4L_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANNRAC_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANPLPR2_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANTM14C_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANT229B_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANTSPO2_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANAPOD_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANTM100_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANVATL_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANSGMR2_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANCLRN2_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANPLPP6_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANASGR1_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANCNIH3_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANCLC7A_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANM4A13_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANDOLK_HUMANBioGRID, IntAct32296183 details
VISTA_HUMANVISTA_HUMANDIP26228159 details