Entity Details

Primary name TLE6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9H808
EntryNameTLE6_HUMAN
FullNameTransducin-like enhancer protein 6
TaxID9606
Evidenceevidence at protein level
Length572
SequenceStatuscomplete
DateCreated2005-04-26
DateModified2021-06-02

Ontological Relatives

GenesTLE6

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005938 cell cortex
GO:0007015 actin filament organization
GO:0032991 protein-containing complex
GO:0040019 positive regulation of embryonic development
GO:0051293 establishment of spindle localization
GO:0051302 regulation of cell division
GO:0051643 endoplasmic reticulum localization
GO:0051646 mitochondrion localization
GO:0060136 embryonic process involved in female pregnancy
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0106333 subcortical maternal complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001680 WD40 repeatRepeatRepeat
IPR009146 Groucho/transducin-like enhancerFamilyFamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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