Entity Details

Primary name MLXPL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NP71
EntryNameMLXPL_HUMAN
FullNameCarbohydrate-responsive element-binding protein
TaxID9606
Evidenceevidence at protein level
Length852
SequenceStatuscomplete
DateCreated2002-01-23
DateModified2021-06-02

Ontological Relatives

GenesMLXIPL

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0008134 transcription factor binding
GO:0008284 positive regulation of cell population proliferation
GO:0009653 anatomical structure morphogenesis
GO:0010255 glucose mediated signaling pathway
GO:0033137 negative regulation of peptidyl-serine phosphorylation
GO:0035538 carbohydrate response element binding
GO:0035556 intracellular signal transduction
GO:0042593 glucose homeostasis
GO:0045723 positive regulation of fatty acid biosynthetic process
GO:0045821 positive regulation of glycolytic process
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046889 positive regulation of lipid biosynthetic process
GO:0046982 protein heterodimerization activity
GO:0055089 fatty acid homeostasis
GO:0070328 triglyceride homeostasis
GO:0090324 negative regulation of oxidative phosphorylation
GO:0097009 energy homeostasis

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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