Entity Details

Primary name ACSA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NR19
EntryNameACSA_HUMAN
FullNameAcetyl-coenzyme A synthetase, cytoplasmic
TaxID9606
Evidenceevidence at protein level
Length701
SequenceStatuscomplete
DateCreated2002-04-03
DateModified2021-06-02

Ontological Relatives

GenesACSS2

GO terms

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GOName
GO:0003987 acetate-CoA ligase activity
GO:0005524 ATP binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005759 mitochondrial matrix
GO:0005829 cytosol
GO:0006069 ethanol oxidation
GO:0008610 lipid biosynthetic process
GO:0016208 AMP binding
GO:0019413 acetate biosynthetic process
GO:0019427 acetyl-CoA biosynthetic process from acetate
GO:0019542 propionate biosynthetic process
GO:0043231 intracellular membrane-bounded organelle
GO:0050218 propionate-CoA ligase activity

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000873 AMP-dependent synthetase/ligaseDomainDomain
IPR011904 Acetate-CoA ligaseFamilyFamily
IPR020845 AMP-binding, conserved siteSiteConserved site
IPR025110 AMP-binding enzyme, C-terminal domainDomainDomain
IPR032387 Acetyl-coenzyme A synthetase, N-terminal domainDomainDomain
IPR042099 ANL, N-terminal domainFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00131 Adenosine phosphateDrugbanksmall molecule
DB00171 ATPDrugbanksmall molecule
DB09395 Sodium acetateSwissprotsmall molecule
DB11936 Bempedoic acidDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ACSA_HUMANRENT1_HUMANBioGRID, HPRD, IntAct15231747 details