Entity Details

Primary name FGF21_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9NSA1
EntryNameFGF21_HUMAN
FullNameFibroblast growth factor 21
TaxID9606
Evidenceevidence at protein level
Length209
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesFGF21

GO terms

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GOName
GO:0001934 positive regulation of protein phosphorylation
GO:0005104 fibroblast growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009887 animal organ morphogenesis
GO:0010628 positive regulation of gene expression
GO:0010898 positive regulation of triglyceride catabolic process
GO:0010988 regulation of low-density lipoprotein particle clearance
GO:0014823 response to activity
GO:0030154 cell differentiation
GO:0030334 regulation of cell migration
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0031667 response to nutrient levels
GO:0035690 cellular response to drug
GO:0046326 positive regulation of glucose import
GO:0070374 positive regulation of ERK1 and ERK2 cascade
GO:0071333 cellular response to glucose stimulus
GO:0071377 cellular response to glucagon stimulus
GO:0071404 cellular response to low-density lipoprotein particle stimulus
GO:0072577 endothelial cell apoptotic process
GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway
GO:0120162 positive regulation of cold-induced thermogenesis
GO:1901215 negative regulation of neuron death
GO:1904640 response to methionine
GO:1905599 positive regulation of low-density lipoprotein receptor activity
GO:2000352 negative regulation of endothelial cell apoptotic process

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002209 Fibroblast growth factor familyFamilyFamily
IPR008996 Cytokine IL1/FGFFamilyHomologous superfamily
IPR028292 Fibroblast growth factor 21FamilyFamily
IPR035444 Fibroblast growth factor 15/19/21FamilyFamily

Diseases

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