Entity Details

Primary name P2RX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UBL9
EntryNameP2RX2_HUMAN
FullNameP2X purinoceptor 2
TaxID9606
Evidenceevidence at protein level
Length471
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesP2RX2

GO terms

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GOName
GO:0001614 purinergic nucleotide receptor activity
GO:0001666 response to hypoxia
GO:0002931 response to ischemia
GO:0003029 detection of hypoxic conditions in blood by carotid body chemoreceptor signaling
GO:0004931 extracellularly ATP-gated cation channel activity
GO:0005524 ATP binding
GO:0005639 integral component of nuclear inner membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007274 neuromuscular synaptic transmission
GO:0007528 neuromuscular junction development
GO:0007596 blood coagulation
GO:0007605 sensory perception of sound
GO:0009743 response to carbohydrate
GO:0010524 positive regulation of calcium ion transport into cytosol
GO:0014832 urinary bladder smooth muscle contraction
GO:0015276 ligand-gated ion channel activity
GO:0016324 apical plasma membrane
GO:0030432 peristalsis
GO:0033198 response to ATP
GO:0042802 identical protein binding
GO:0043025 neuronal cell body
GO:0043235 receptor complex
GO:0048266 behavioral response to pain
GO:0048741 skeletal muscle fiber development
GO:0050850 positive regulation of calcium-mediated signaling
GO:0050909 sensory perception of taste
GO:0098794 postsynapse

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001429 P2X purinoreceptorFamilyFamily
IPR003045 P2X2 purinoceptorFamilyFamily
IPR027309 P2X purinoreceptor extracellular domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01069 PromethazineDrugbanksmall molecule