Entity Details

Primary name ST17A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UEE5
EntryNameST17A_HUMAN
FullNameSerine/threonine-protein kinase 17A
TaxID9606
Evidenceevidence at protein level
Length414
SequenceStatuscomplete
DateCreated2001-06-20
DateModified2021-06-02

Ontological Relatives

GenesSTK17A

GO terms

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GOName
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0006468 protein phosphorylation
GO:0006915 apoptotic process
GO:0016607 nuclear speck
GO:0035556 intracellular signal transduction
GO:0043065 positive regulation of apoptotic process
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:2000271 positive regulation of fibroblast apoptotic process
GO:2000377 regulation of reactive oxygen species metabolic process

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR042704 Serine/threonine-protein kinase 17A, catalytic domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB12010 FostamatinibDrugbanksmall molecule

Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ST17A_HUMANST17A_HUMANBioGRID, HPRD9786912 details
ST17A_HUMANTRAF6_HUMANBioGRID32265222 details
ST17A_HUMANSQSTM_HUMANBioGRID32265222 details