Entity Details

Primary name BARX2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UMQ3
EntryNameBARX2_HUMAN
FullNameHomeobox protein BarH-like 2
TaxID9606
Evidenceevidence at protein level
Length279
SequenceStatuscomplete
DateCreated2001-04-27
DateModified2021-06-02

Ontological Relatives

GenesBARX2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001502 cartilage condensation
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0006357 regulation of transcription by RNA polymerase II
GO:0014902 myotube differentiation
GO:0015629 actin cytoskeleton
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000047 Helix-turn-helix motifSiteConserved site
IPR001356 Homeobox domainDomainDomain
IPR009057 Homeobox-like domain superfamilyFamilyHomologous superfamily
IPR017970 Homeobox, conserved siteSiteConserved site
IPR020479 Homeobox domain, metazoaDomainDomain

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
BARX2_HUMANFHL2_HUMANBioGRID, IntAct32296183 details
BARX2_HUMANFHL3_HUMANBioGRID, IntAct32296183 details
BARX2_HUMANSRF_HUMANHPRD11278942 details