Entity Details

Primary name XCT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9UPY5
EntryNameXCT_HUMAN
FullNameCystine/glutamate transporter
TaxID9606
Evidenceevidence at protein level
Length501
SequenceStatuscomplete
DateCreated2001-01-24
DateModified2021-06-02

Ontological Relatives

GenesSLC7A11

GO terms

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GOName
GO:0005791 rough endoplasmic reticulum
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0006749 glutathione metabolic process
GO:0006865 amino acid transport
GO:0008542 visual learning
GO:0009636 response to toxic substance
GO:0009986 cell surface
GO:0014070 response to organic cyclic compound
GO:0015179 L-amino acid transmembrane transporter activity
GO:0015327 cystine:glutamate antiporter activity
GO:0016021 integral component of membrane
GO:0021591 ventricular system development
GO:0021756 striatum development
GO:0030534 adult behavior
GO:0031526 brush border membrane
GO:0033029 regulation of neutrophil apoptotic process
GO:0034599 cellular response to oxidative stress
GO:0034775 glutathione transmembrane transport
GO:0035094 response to nicotine
GO:0042127 regulation of cell population proliferation
GO:0045177 apical part of cell
GO:0048021 regulation of melanin biosynthetic process
GO:0048286 lung alveolus development
GO:0050804 modulation of chemical synaptic transmission
GO:0050807 regulation of synapse organization
GO:0050900 leukocyte migration
GO:0051223 regulation of protein transport
GO:0051775 response to redox state
GO:0060173 limb development
GO:0070306 lens fiber cell differentiation
GO:0070527 platelet aggregation
GO:0090461 glutamate homeostasis
GO:0097449 astrocyte projection
GO:0098712 L-glutamate import across plasma membrane
GO:0140206 dipeptide import across plasma membrane
GO:1901494 regulation of cysteine metabolic process
GO:1903204 negative regulation of oxidative stress-induced neuron death
GO:1903786 regulation of glutathione biosynthetic process
GO:1904717 regulation of AMPA glutamate receptor clustering
GO:2000211 regulation of glutamate metabolic process

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR002293 Amino acid/polyamine transporter IFamilyFamily
IPR004760 L-type amino acid transporterFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB00138 CystineDrugbanksmall molecule
DB00142 Glutamic acidDrugbanksmall molecule
DB00740 RiluzoleDrugbanksmall molecule
DB00795 SulfasalazineDrugbanksmall molecule
DB01098 RosuvastatinDrugbanksmall molecule
DB04348 Taurocholic acidDrugbanksmall molecule
DB05540 AlanosineDrugbanksmall molecule
DB06151 AcetylcysteineDrugbanksmall molecule
DB08833 Taurochenodeoxycholic acidSwissprotsmall molecule
DB08834 Tauroursodeoxycholic acidSwissprotsmall molecule
DB11590 ThimerosalDrugbanksmall molecule