Entity Details

Primary name AKT3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ9Y243
EntryNameAKT3_HUMAN
FullNameRAC-gamma serine/threonine-protein kinase
TaxID9606
Evidenceevidence at protein level
Length479
SequenceStatuscomplete
DateCreated2000-12-01
DateModified2021-06-02

Ontological Relatives

GenesAKT3

GO terms

Show/Hide Table
GOName
GO:0000002 mitochondrial genome maintenance
GO:0001938 positive regulation of endothelial cell proliferation
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006468 protein phosphorylation
GO:0007165 signal transduction
GO:0016020 membrane
GO:0018105 peptidyl-serine phosphorylation
GO:0032008 positive regulation of TOR signaling
GO:0035556 intracellular signal transduction
GO:0043536 positive regulation of blood vessel endothelial cell migration
GO:0045766 positive regulation of angiogenesis
GO:0045793 positive regulation of cell size
GO:0048854 brain morphogenesis
GO:0048873 homeostasis of number of cells within a tissue
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:0106310 protein serine kinase activity
GO:0106311 protein threonine kinase activity
GO:1905564 positive regulation of vascular endothelial cell proliferation
GO:1905653 positive regulation of artery morphogenesis
GO:2000773 negative regulation of cellular senescence

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Membrane
Nucleus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR000961 AGC-kinase, C-terminalDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR008271 Serine/threonine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR017892 Protein kinase, C-terminalDomainDomain
IPR034675 Protein kinase B gamma, catalytic domainDomainDomain
IPR039026 Protein Kinase B, pleckstrin homology domainDomainDomain
IPR039029 Serine/threonine-protein kinase RAC gamma-likeFamilyFamily

Diseases

Show/Hide Table