Entity Details
| Primary name |
SO1B1_HUMAN |
| Entity type |
UniProt |
| Source |
Source Link |
Details
| Accession | Q9Y6L6 |
| EntryName | SO1B1_HUMAN |
| FullName | Solute carrier organic anion transporter family member 1B1 |
| TaxID | 9606 |
| Evidence | evidence at protein level |
| Length | 691 |
| SequenceStatus | complete |
| DateCreated | 2000-12-01 |
| DateModified | 2021-06-02 |
Subcellular Location
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| Subcellular Location |
| Basolateral cell membrane |
Domains
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| Domain | Name | Category | Type |
| IPR002350 | Kazal domain | Domain | Domain |
| IPR004156 | Organic anion transporter polypeptide | Family | Family |
| IPR020846 | Major facilitator superfamily domain | Domain | Domain |
| IPR036058 | Kazal domain superfamily | Family | Homologous superfamily |
| IPR036259 | MFS transporter superfamily | Family | Homologous superfamily |
Diseases
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| Disease ID | Source | Name | Description |
| 237450 | OMIM | Hyperbilirubinemia, Rotor type (HBLRR) | An autosomal recessive form of primary conjugated hyperbilirubinemia. Affected individuals develop mild jaundice not associated with hemolysis shortly after birth or in childhood. They have delayed plasma clearance of the unconjugated anionic dye bromsulphthalein and prominent urinary excretion of coproporphyrin I. Hepatic pigmentation is normal. The disease is caused by variants affecting the gene represented in this entry. |
Drugs
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| Drug | Name | Source | Type |
| DB00091 | Cyclosporine | Drugbank | small molecule |
| DB00175 | Pravastatin | Drugbank | small molecule |
| DB00177 | Valsartan | Drugbank | small molecule |
| DB00197 | Troglitazone | Drugbank | small molecule |
| DB00199 | Erythromycin | Drugbank | small molecule |
| DB00203 | Sildenafil | Drugbank | small molecule |
| DB00206 | Reserpine | Drugbank | small molecule |
| DB00214 | Torasemide | Drugbank | small molecule |
| DB00220 | Nelfinavir | Drugbank | small molecule |
| DB00224 | Indinavir | Drugbank | small molecule |
| DB00227 | Lovastatin | Drugbank | small molecule |
| DB00255 | Diethylstilbestrol | Drugbank | small molecule |
| DB00257 | Clotrimazole | Drugbank | small molecule |
| DB00275 | Olmesartan | Drugbank | small molecule |
| DB00279 | Liothyronine | Drugbank | small molecule |
| DB00286 | Conjugated estrogens | Drugbank | small molecule |
| DB00328 | Indomethacin | Drugbank | small molecule |
| DB00345 | Aminohippuric acid | Swissprot | small molecule |
| DB00390 | Digoxin | Drugbank | small molecule |
| DB00394 | Beclomethasone dipropionate | Drugbank | small molecule |
| DB00396 | Progesterone | Drugbank | small molecule |
| DB00398 | Sorafenib | Drugbank | small molecule |
| DB00412 | Rosiglitazone | Drugbank | small molecule |
| DB00439 | Cerivastatin | Drugbank | small molecule |
| DB00451 | Levothyroxine | Drugbank | small molecule |
| DB00468 | Quinine | Drugbank | small molecule |
| DB00481 | Raloxifene | Drugbank | small molecule |
| DB00503 | Ritonavir | Drugbank | small molecule |
| DB00509 | Dextrothyroxine | Drugbank | small molecule |
| DB00520 | Caspofungin | Drugbank | small molecule |
| DB00541 | Vincristine | Drugbank | small molecule |
| DB00563 | Methotrexate | Drugbank | small molecule |
| DB00570 | Vinblastine | Drugbank | small molecule |
| DB00583 | Levocarnitine | Drugbank | small molecule |
| DB00586 | Diclofenac | Drugbank | small molecule |
| DB00588 | Fluticasone propionate | Drugbank | small molecule |
| DB00602 | Ivermectin | Drugbank | small molecule |
| DB00622 | Nicardipine | Drugbank | small molecule |
| DB00641 | Simvastatin | Drugbank | small molecule |
| DB00646 | Nystatin | Swissprot | small molecule |
| DB00655 | Estrone | Drugbank | small molecule |
| DB00661 | Verapamil | Drugbank | small molecule |
| DB00669 | Sumatriptan | Drugbank | small molecule |
| DB00688 | Mycophenolate mofetil | Drugbank | small molecule |
| DB00701 | Amprenavir | Drugbank | small molecule |
| DB00762 | Irinotecan | Drugbank | small molecule |
| DB00783 | Estradiol | Drugbank | small molecule |
| DB00795 | Sulfasalazine | Drugbank | small molecule |
| DB00834 | Mifepristone | Drugbank | small molecule |
| DB00859 | Penicillamine | Swissprot | small molecule |
| DB00864 | Tacrolimus | Drugbank | small molecule |
| DB00877 | Sirolimus | Drugbank | small molecule |
| DB00908 | Quinidine | Drugbank | small molecule |
| DB00912 | Repaglinide | Drugbank | small molecule |
| DB00917 | Dinoprostone | Drugbank | small molecule |
| DB00932 | Tipranavir | Drugbank | small molecule |
| DB00950 | Fexofenadine | Drugbank | small molecule |
| DB00973 | Ezetimibe | Drugbank | small molecule |
| DB00975 | Dipyridamole | Drugbank | small molecule |
| DB00976 | Telithromycin | Swissprot | small molecule |
| DB01026 | Ketoconazole | Drugbank | small molecule |
| DB01045 | Rifampicin | Drugbank | small molecule |
| DB01051 | Novobiocin | Drugbank | small molecule |
| DB01053 | Benzylpenicillin | Drugbank | small molecule |
| DB01072 | Atazanavir | Drugbank | small molecule |
| DB01076 | Atorvastatin | Drugbank | small molecule |
| DB01092 | Ouabain | Drugbank | small molecule |
| DB01095 | Fluvastatin | Drugbank | small molecule |
| DB01098 | Rosuvastatin | Drugbank | small molecule |
| DB01115 | Nifedipine | Drugbank | small molecule |
| DB01132 | Pioglitazone | Drugbank | small molecule |
| DB01211 | Clarithromycin | Drugbank | small molecule |
| DB01232 | Saquinavir | Drugbank | small molecule |
| DB01241 | Gemfibrozil | Drugbank | small molecule |
| DB01264 | Darunavir | Drugbank | small molecule |
| DB01393 | Bezafibrate | Drugbank | small molecule |
| DB01583 | Liotrix | Drugbank | small molecule |
| DB01590 | Everolimus | Drugbank | small molecule |
| DB01601 | Lopinavir | Drugbank | small molecule |
| DB01645 | Genistein | Drugbank | small molecule |
| DB01708 | Prasterone | Drugbank | small molecule |
| DB01892 | Hyperforin | Drugbank | small molecule |
| DB02659 | Cholic Acid | Drugbank | small molecule |
| DB02691 | Glycocholic acid | Drugbank | small molecule |
| DB02703 | Fusidic acid | Drugbank | small molecule |
| DB04216 | Quercetin | Drugbank | small molecule |
| DB04348 | Taurocholic acid | Drugbank | small molecule |
| DB04850 | Posizolid | Drugbank | small molecule |
| DB04855 | Dronedarone | Drugbank | small molecule |
| DB04868 | Nilotinib | Drugbank | small molecule |
| DB05239 | Cobimetinib | Drugbank | small molecule |
| DB05521 | Telaprevir | Drugbank | small molecule |
| DB05804 | Prasterone sulfate | Swissprot | small molecule |
| DB05928 | Dovitinib | Drugbank | small molecule |
| DB06137 | Tirbanibulin | Drugbank | small molecule |
| DB06151 | Acetylcysteine | Drugbank | small molecule |
| DB06210 | Eltrombopag | Drugbank | small molecule |
| DB06290 | Simeprevir | Drugbank | small molecule |
| DB06403 | Ambrisentan | Drugbank | small molecule |
| DB06448 | Lonafarnib | Drugbank | small molecule |
| DB06589 | Pazopanib | Drugbank | small molecule |
| DB06626 | Axitinib | Drugbank | small molecule |
| DB06721 | Gimatecan | Swissprot | small molecule |
| DB06772 | Cabazitaxel | Drugbank | small molecule |
| DB08855 | Leukotriene C4 | Drugbank | small molecule |
| DB08856 | DADLE | Swissprot | small molecule |
| DB08857 | Bamet-UD2 | Swissprot | small molecule |
| DB08858 | cis-Diamminechlorocholylglycinateplatinum(II) | Swissprot | small molecule |
| DB08860 | Pitavastatin | Drugbank | small molecule |
| DB08862 | Cholecystokinin | Drugbank | small molecule |
| DB08864 | Rilpivirine | Drugbank | small molecule |
| DB08880 | Teriflunomide | Drugbank | small molecule |
| DB08884 | Gadoxetic acid | Swissprot | small molecule |
| DB08906 | Fluticasone furoate | Drugbank | small molecule |
| DB08912 | Dabrafenib | Drugbank | small molecule |
| DB09038 | Empagliflozin | Drugbank | small molecule |
| DB09054 | Idelalisib | Drugbank | small molecule |
| DB09065 | Cobicistat | Swissprot | small molecule |
| DB09078 | Lenvatinib | Drugbank | small molecule |
| DB09102 | Daclatasvir | Drugbank | small molecule |
| DB09137 | Technetium Tc-99m mebrofenin | Swissprot | small molecule |
| DB09198 | Lobeglitazone | Drugbank | small molecule |
| DB09272 | Eluxadoline | Drugbank | small molecule |
| DB09274 | Artesunate | Drugbank | small molecule |
| DB09279 | Fimasartan | Drugbank | small molecule |
| DB09292 | Sacubitril | Drugbank | small molecule |
| DB09297 | Paritaprevir | Drugbank | small molecule |
| DB09298 | Silibinin | Swissprot | small molecule |
| DB09299 | Tenofovir alafenamide | Drugbank | small molecule |
| DB11362 | Selexipag | Drugbank | small molecule |
| DB11575 | Grazoprevir | Drugbank | small molecule |
| DB11581 | Venetoclax | Drugbank | small molecule |
| DB11586 | Asunaprevir | Drugbank | small molecule |
| DB11613 | Velpatasvir | Drugbank | small molecule |
| DB11753 | Rifamycin | Drugbank | small molecule |
| DB11757 | Istradefylline | Drugbank | small molecule |
| DB11796 | Fostemsavir | Drugbank | small molecule |
| DB11837 | Osilodrostat | Drugbank | small molecule |
| DB11855 | Revefenacin | Drugbank | small molecule |
| DB11869 | Valspodar | Swissprot | small molecule |
| DB11901 | Apalutamide | Drugbank | small molecule |
| DB11936 | Bempedoic acid | Drugbank | small molecule |
| DB11979 | Elagolix | Drugbank | small molecule |
| DB12026 | Voxilaprevir | Drugbank | small molecule |
| DB12070 | Letermovir | Drugbank | small molecule |
| DB12319 | Benzbromarone | Drugbank | small molecule |
| DB12332 | Rucaparib | Drugbank | small molecule |
| DB12457 | Rimegepant | Drugbank | small molecule |
| DB12500 | Fedratinib | Drugbank | small molecule |
| DB12674 | Lurbinectedin | Swissprot | small molecule |
| DB12941 | Darolutamide | Drugbank | small molecule |
| DB12978 | Pexidartinib | Drugbank | small molecule |
| DB13139 | Levosalbutamol | Drugbank | small molecule |
| DB13153 | Levomenol | Swissprot | small molecule |
| DB13867 | Fluticasone | Drugbank | small molecule |
| DB13874 | Enasidenib | Drugbank | small molecule |
| DB13878 | Pibrentasvir | Drugbank | small molecule |
| DB13879 | Glecaprevir | Drugbank | small molecule |
| DB13919 | Candesartan | Drugbank | small molecule |
| DB13952 | Estradiol acetate | Drugbank | small molecule |
| DB13953 | Estradiol benzoate | Drugbank | small molecule |
| DB13954 | Estradiol cypionate | Drugbank | small molecule |
| DB13955 | Estradiol dienanthate | Drugbank | small molecule |
| DB13956 | Estradiol valerate | Drugbank | small molecule |
| DB14761 | Remdesivir | Drugbank | small molecule |
| DB14962 | Trastuzumab deruxtecan | Drugbank | biotech |
| DB15091 | Upadacitinib | Drugbank | small molecule |
| DB15328 | Ubrogepant | Drugbank | small molecule |
| DB15444 | Elexacaftor | Drugbank | small molecule |
| DB15719 | Belantamab mafodotin | Drugbank | biotech |
| DB15822 | Pralsetinib | Drugbank | small molecule |
Interactions
0 interactions
| Interactor | Partner | Sources | Publications | Link |