Entity Details

Primary name FZD6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO60353
EntryNameFZD6_HUMAN
FullNameFrizzled-6
TaxID9606
Evidenceevidence at protein level
Length706
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesFZD6

GO terms

Show/Hide Table
GOName
GO:0001843 neural tube closure
GO:0001942 hair follicle development
GO:0004930 G protein-coupled receptor activity
GO:0005789 endoplasmic reticulum membrane
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007223 Wnt signaling pathway, calcium modulating pathway
GO:0009986 cell surface
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0016327 apicolateral plasma membrane
GO:0017147 Wnt-protein binding
GO:0030168 platelet activation
GO:0030659 cytoplasmic vesicle membrane
GO:0031625 ubiquitin protein ligase binding
GO:0033278 cell proliferation in midbrain
GO:0035567 non-canonical Wnt signaling pathway
GO:0035880 embryonic nail plate morphogenesis
GO:0042472 inner ear morphogenesis
GO:0042813 Wnt-activated receptor activity
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0048105 establishment of body hair planar orientation
GO:0060070 canonical Wnt signaling pathway
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1904693 midbrain morphogenesis

Subcellular Location

Show/Hide Table
Subcellular Location
Apical cell membrane
Cell membrane
Cell surface
Cytoplasmic vesicle membrane
Endoplasmic reticulum membrane
Membrane

Domains

Show/Hide Table
DomainNameCategoryType
IPR000539 Frizzled/Smoothened, transmembrane domainDomainDomain
IPR015526 Frizzled/secreted frizzled-related proteinFamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR020067 Frizzled domainDomainDomain
IPR026543 Frizzled-6FamilyFamily
IPR036790 Frizzled cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR041770 Frizzled 6, cysteine-rich domainDomainDomain

Diseases

Show/Hide Table

Interactions

5 interactions