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Entity Details
Primary name
DDAH2_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
O95865
EntryName
DDAH2_HUMAN
FullName
N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
TaxID
9606
Evidence
evidence at protein level
Length
285
SequenceStatus
complete
DateCreated
2000-05-30
DateModified
2021-06-02
Ontological Relatives
Genes
DDAH2
GO terms
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GO
Name
GO:0000052
citrulline metabolic process
GO:0003824
catalytic activity
GO:0005739
mitochondrion
GO:0005829
cytosol
GO:0006525
arginine metabolic process
GO:0006527
arginine catabolic process
GO:0006809
nitric oxide biosynthetic process
GO:0007263
nitric oxide mediated signal transduction
GO:0016403
dimethylargininase activity
GO:0016597
amino acid binding
GO:0043066
negative regulation of apoptotic process
GO:0045429
positive regulation of nitric oxide biosynthetic process
GO:0050999
regulation of nitric-oxide synthase activity
GO:0070062
extracellular exosome
Subcellular Location
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Subcellular Location
Cytoplasm
Mitochondrion
Domains
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Domain
Name
Category
Type
IPR033199
Dimethylarginine dimethylaminohydrolase
Family
Family
IPR033202
N(G),N(G)-dimethylarginine dimethylaminohydrolase 2
Family
Family
Diseases
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Drugs
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Drug
Name
Source
Type
DB00155
Citrulline
Drugbank
small molecule
Interactions
28 interactions
Interactor
Partner
Sources
Publications
Link
DDAH2_HUMAN
PCH2_HUMAN
BioGRID, HPRD, IntAct
16189514
19060904
32296183
details
DDAH2_HUMAN
ANXA7_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
AT1B1_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
CDC73_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
CDK4_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
CDN1A_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
DJB11_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
GA45G_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
MKNK1_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
PIN1_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
RAP1B_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
RCC1_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
KS6A1_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
KS6A5_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
SMN_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
STK3_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
TAF1D_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
KITH_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
TNF11_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
T22D1_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
M3K20_HUMAN
BioGRID, MINT
21900206
details
DDAH2_HUMAN
IGFN1_HUMAN
BioGRID, IntAct
32296183
details
DDAH2_HUMAN
ACTN3_HUMAN
BioGRID, IntAct
32296183
details
DDAH2_HUMAN
AAKB2_HUMAN
BioGRID, IntAct
32296183
details
DDAH2_HUMAN
NOXA1_HUMAN
BioGRID, IntAct
32296183
details
DDAH2_HUMAN
FANCL_HUMAN
BioGRID, IntAct
32296183
details
DDAH2_HUMAN
VAC14_HUMAN
BioGRID, IntAct
25416956
29892012
details
DDAH2_HUMAN
SEGN_HUMAN
BioGRID
21528130
details
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