Entity Details

Primary name APCL_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionO95996
EntryNameAPCL_HUMAN
FullNameAdenomatous polyposis coli protein 2
TaxID9606
Evidenceevidence at protein level
Length2303
SequenceStatuscomplete
DateCreated2008-01-15
DateModified2021-06-02

Ontological Relatives

GenesAPC2

GO terms

Show/Hide Table
GOName
GO:0000226 microtubule cytoskeleton organization
GO:0001708 cell fate specification
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005884 actin filament
GO:0007026 negative regulation of microtubule depolymerization
GO:0007389 pattern specification process
GO:0007399 nervous system development
GO:0008013 beta-catenin binding
GO:0008017 microtubule binding
GO:0015630 microtubule cytoskeleton
GO:0016055 Wnt signaling pathway
GO:0016342 catenin complex
GO:0016477 cell migration
GO:0030496 midbody
GO:0030877 beta-catenin destruction complex
GO:0031258 lamellipodium membrane
GO:0045171 intercellular bridge
GO:0045295 gamma-catenin binding
GO:0045595 regulation of cell differentiation
GO:0045732 positive regulation of protein catabolic process
GO:0048471 perinuclear region of cytoplasm
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090630 activation of GTPase activity
GO:0098794 postsynapse

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Golgi apparatus

Domains

Show/Hide Table
DomainNameCategoryType
IPR000225 ArmadilloRepeatRepeat
IPR009223 Adenomatous polyposis coli protein repeatRepeatRepeat
IPR009224 SAMPRepeatRepeat
IPR009234 Adenomatous polyposis coli protein basic domainDomainDomain
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR026818 Adenomatous polyposis coli (APC) familyFamilyFamily
IPR026831 Adenomatous polyposis coli proteinFamilyHomologous superfamily
IPR026837 Adenomatous polyposis coli 2FamilyFamily
IPR032038 Adenomatous polyposis coli, N-terminal dimerisation domainDomainDomain
IPR036149 APC, N-terminal coiled-coil domain superfamilyFamilyHomologous superfamily
IPR041257 Adenomatous polyposis coli (APC) repeatRepeatRepeat

Diseases

Show/Hide Table