Entity Details

Primary name HPT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP00738
EntryNameHPT_HUMAN
FullNameHaptoglobin
TaxID9606
Evidenceevidence at protein level
Length406
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesHP

GO terms

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GOName
GO:0002526 acute inflammatory response
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006898 receptor-mediated endocytosis
GO:0006952 defense response
GO:0006953 acute-phase response
GO:0010942 positive regulation of cell death
GO:0016209 antioxidant activity
GO:0030492 hemoglobin binding
GO:0031638 zymogen activation
GO:0031838 haptoglobin-hemoglobin complex
GO:0035580 specific granule lumen
GO:0042542 response to hydrogen peroxide
GO:0042742 defense response to bacterium
GO:0043312 neutrophil degranulation
GO:0051354 negative regulation of oxidoreductase activity
GO:0070062 extracellular exosome
GO:0071682 endocytic vesicle lumen
GO:0072562 blood microparticle
GO:1904724 tertiary granule lumen
GO:2000296 negative regulation of hydrogen peroxide catabolic process

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR000436 Sushi/SCR/CCP domainDomainDomain
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR008292 HaptoglobinFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR035976 Sushi/SCR/CCP superfamilyFamilyHomologous superfamily
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule