Entity Details

Primary name ANF_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP01160
EntryNameANF_HUMAN
FullNameNatriuretic peptides A
TaxID9606
Evidenceevidence at protein level
Length151
SequenceStatuscomplete
DateCreated1986-07-21
DateModified2021-06-02

Ontological Relatives

GenesNPPA

GO terms

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GOName
GO:0003085 negative regulation of systemic arterial blood pressure
GO:0003161 cardiac conduction system development
GO:0003180 aortic valve morphogenesis
GO:0005102 signaling receptor binding
GO:0005179 hormone activity
GO:0005184 neuropeptide hormone activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006182 cGMP biosynthetic process
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0006457 protein folding
GO:0007168 receptor guanylyl cyclase signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0007565 female pregnancy
GO:0008217 regulation of blood pressure
GO:0010460 positive regulation of heart rate
GO:0019934 cGMP-mediated signaling
GO:0032991 protein-containing complex
GO:0035994 response to muscle stretch
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042311 vasodilation
GO:0042995 cell projection
GO:0043204 perikaryon
GO:0043508 negative regulation of JUN kinase activity
GO:0051427 hormone receptor binding
GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization
GO:0060452 positive regulation of cardiac muscle contraction
GO:0062023 collagen-containing extracellular matrix
GO:0071855 neuropeptide receptor binding
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:1901841 regulation of high voltage-gated calcium channel activity
GO:1902261 positive regulation of delayed rectifier potassium channel activity
GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
GO:1903766 positive regulation of potassium ion export across plasma membrane
GO:1903779 regulation of cardiac conduction
GO:1990000 amyloid fibril formation

Subcellular Location

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Subcellular Location
Cell projection
Perikaryon
Secreted

Domains

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DomainNameCategoryType
IPR000663 Natriuretic peptideFamilyFamily
IPR002407 Natriuretic peptide, atrial typeFamilyFamily
IPR030480 Natriuretic peptide, conserved siteSiteConserved site

Diseases

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