Entity Details

Primary name APT_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP07741
EntryNameAPT_HUMAN
FullNameAdenine phosphoribosyltransferase
TaxID9606
Evidenceevidence at protein level
Length180
SequenceStatuscomplete
DateCreated1988-08-01
DateModified2021-06-02

Ontological Relatives

GenesAPRT

GO terms

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GOName
GO:0002055 adenine binding
GO:0003999 adenine phosphoribosyltransferase activity
GO:0005576 extracellular region
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006166 purine ribonucleoside salvage
GO:0006168 adenine salvage
GO:0007595 lactation
GO:0007625 grooming behavior
GO:0016208 AMP binding
GO:0032869 cellular response to insulin stimulus
GO:0034774 secretory granule lumen
GO:0043101 purine-containing compound salvage
GO:0043312 neutrophil degranulation
GO:0044209 AMP salvage
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000836 Phosphoribosyltransferase domainDomainDomain
IPR005764 Adenine phosphoribosyl transferaseFamilyFamily
IPR029057 Phosphoribosyltransferase-likeFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00131 Adenosine phosphateDrugbanksmall molecule
DB00173 AdenineDrugbanksmall molecule
DB01632 5-O-phosphono-alpha-D-ribofuranosyl diphosphateDrugbanksmall molecule
DB03506 9-DeazaadenineDrugbanksmall molecule
DB04272 Citric acidDrugbanksmall molecule