Entity Details

Primary name CSF3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP09919
EntryNameCSF3_HUMAN
FullNameGranulocyte colony-stimulating factor
TaxID9606
Evidenceevidence at protein level
Length207
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesCSF3

GO terms

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GOName
GO:0005125 cytokine activity
GO:0005130 granulocyte colony-stimulating factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006955 immune response
GO:0007275 multicellular organism development
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0019221 cytokine-mediated signaling pathway
GO:0019899 enzyme binding
GO:0030838 positive regulation of actin filament polymerization
GO:0030851 granulocyte differentiation
GO:0032092 positive regulation of protein binding
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0045471 response to ethanol
GO:0045639 positive regulation of myeloid cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0051897 positive regulation of protein kinase B signaling
GO:0071222 cellular response to lipopolysaccharide
GO:0071345 cellular response to cytokine stimulus
GO:1901215 negative regulation of neuron death
GO:2000251 positive regulation of actin cytoskeleton reorganization

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily
IPR030473 Interleukin-6/GCSF/MGF, conserved siteSiteConserved site
IPR030474 Interleukin-6/GCSF/MGFFamilyFamily
IPR040117 GCSF/MGFFamilyFamily

Diseases

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Interactions

4 interactions