Entity Details

Primary name RAP2A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP10114
EntryNameRAP2A_HUMAN
FullNameRas-related protein Rap-2a
TaxID9606
Evidenceevidence at protein level
Length183
SequenceStatuscomplete
DateCreated1989-07-01
DateModified2021-06-02

Ontological Relatives

GenesRAP2A

GO terms

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GOName
GO:0000287 magnesium ion binding
GO:0001934 positive regulation of protein phosphorylation
GO:0003924 GTPase activity
GO:0003925 G protein activity
GO:0005525 GTP binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0019003 GDP binding
GO:0030033 microvillus assembly
GO:0030336 negative regulation of cell migration
GO:0030496 midbody
GO:0031532 actin cytoskeleton reorganization
GO:0031954 positive regulation of protein autophosphorylation
GO:0032486 Rap protein signal transduction
GO:0034613 cellular protein localization
GO:0035690 cellular response to drug
GO:0045184 establishment of protein localization
GO:0046328 regulation of JNK cascade
GO:0048814 regulation of dendrite morphogenesis
GO:0055037 recycling endosome
GO:0055038 recycling endosome membrane
GO:0072659 protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Midbody
Recycling endosome membrane

Domains

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DomainNameCategoryType
IPR001806 Small GTPaseFamilyFamily
IPR005225 Small GTP-binding protein domainDomainDomain
IPR020849 Small GTPase, Ras-typeFamilyFamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR041840 Ras-related protein Rap2FamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB04137 Guanosine-5'-TriphosphateDrugbanksmall molecule
DB04315 Guanosine-5'-DiphosphateDrugbanksmall molecule

Interactions

35 interactions

InteractorPartnerSourcesPublicationsLink
RAP2A_HUMANPLMN_HUMANBioGRID, IntAct18624398 details
RAP2A_HUMANFKBP2_HUMANBioGRID, IntAct18624398 details
RAP2A_HUMANEF1A1_HUMANBioGRID, IntAct18624398 details
RAP2A_HUMANU3IP2_HUMANBioGRID, IntAct18624398 details
RAP2A_HUMANERG24_HUMANBioGRID, IntAct18624398 details
RAP2A_HUMANA1AT_HUMANBioGRID, IntAct18624398 details
RAP2A_HUMANFRIL_HUMANBioGRID, IntAct18624398 details
RAP2A_HUMANENSA_HUMANBioGRID, IntAct18624398 details
RAP2A_HUMANMINK1_HUMANIntAct18930710 details
RAP2A_HUMANRUN3A_HUMANBioGRID, HPRD, IntAct32296183 9523700 details
RAP2A_HUMANRGL1_HUMANBioGRID, IntAct32296183 details
RAP2A_HUMANEMP3_HUMANMINT30614533 details
RAP2A_HUMANGBRL2_HUMANBioGRID12581858 details
RAP2A_HUMANRPGF3_HUMANBioGRID10777494 details
RAP2A_HUMANRPGF4_HUMANBioGRID10777494 details
RAP2A_HUMANRPGF5_HUMANBioGRID, HPRD10777494 details
RAP2A_HUMANRASF5_HUMANBioGRID, HPRD11857081 details
RAP2A_HUMANRGS14_HUMANBioGRID, HPRD10926822 details
RAP2A_HUMANGNDS_HUMANBioGRID, HPRD10085114 11786539 28405688 details
RAP2A_HUMANRPGF6_HUMANBioGRID, HPRD11524421 12581858 details
RAP2A_HUMANNEDD4_HUMANBioGRID20159449 28405688 details
RAP2A_HUMANRAIN_HUMANHPRD15031288 details
RAP2A_HUMANTNIK_HUMANHPRD15342639 details
RAP2A_HUMANRHG29_HUMANHPRD15752761 details
RAP2A_HUMANM4K4_HUMANHPRD14966141 details
RAP2A_HUMANRAF1_HUMANHPRD9523700 details
RAP2A_HUMANMTOR_HUMANBioGRID25446900 details
RAP2A_HUMANRAP2A_HUMANHPRD10224125 details
RAP2A_HUMANNMDE4_HUMANHPRD10862698 details
RAP2A_HUMANNMDZ1_HUMANHPRD10862698 details
RAP2A_HUMANACVR1_HUMANHPRD15761153 details
RAP2A_HUMANBMR1B_HUMANHPRD15761153 details
RAP2A_HUMANSMAD1_HUMANHPRD15761153 details
RAP2A_HUMANTGFR1_HUMANHPRD15761153 details
RAP2A_HUMANFNTB_HUMANHPRD15451670 details