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Entity Details
Primary name
MLRV_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P10916
EntryName
MLRV_HUMAN
FullName
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform
TaxID
9606
Evidence
evidence at protein level
Length
166
SequenceStatus
complete
DateCreated
1989-07-01
DateModified
2021-06-02
Ontological Relatives
Genes
MYL2
GO terms
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GO
Name
GO:0002026
regulation of the force of heart contraction
GO:0003785
actin monomer binding
GO:0005509
calcium ion binding
GO:0005829
cytosol
GO:0005856
cytoskeleton
GO:0006942
regulation of striated muscle contraction
GO:0007507
heart development
GO:0008307
structural constituent of muscle
GO:0016459
myosin complex
GO:0030016
myofibril
GO:0030017
sarcomere
GO:0030049
muscle filament sliding
GO:0030308
negative regulation of cell growth
GO:0031672
A band
GO:0032036
myosin heavy chain binding
GO:0055003
cardiac myofibril assembly
GO:0055010
ventricular cardiac muscle tissue morphogenesis
GO:0060047
heart contraction
GO:0097512
cardiac myofibril
GO:0098735
positive regulation of the force of heart contraction
Subcellular Location
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Subcellular Location
Cytoplasm
Domains
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Domain
Name
Category
Type
IPR002048
EF-hand domain
Domain
Domain
IPR011992
EF-hand domain pair
Family
Homologous superfamily
IPR018247
EF-Hand 1, calcium-binding site
Site
Binding site
Diseases
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Drugs
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Interactions
14 interactions
Interactor
Partner
Sources
Publications
Link
MLRV_HUMAN
LRSM1_HUMAN
HPRD, IntAct
16169070
details
MLRV_HUMAN
UBP6_HUMAN
BioGRID, HPRD, IntAct
16555005
details
MLRV_HUMAN
CXB5_HUMAN
BioGRID, IntAct
21988832
details
MLRV_HUMAN
NHP2_HUMAN
BioGRID, IntAct
21988832
details
MLRV_HUMAN
ZN529_HUMAN
BioGRID, IntAct
27107012
details
MLRV_HUMAN
IRX6_HUMAN
IntAct
32296183
details
MLRV_HUMAN
PS1C2_HUMAN
BioGRID, IntAct
32296183
details
MLRV_HUMAN
MYOC_HUMAN
HPRD, UniProt
11773029
details
MLRV_HUMAN
PAK2_HUMAN
BioGRID, HPRD
10047984
details
MLRV_HUMAN
TRI63_HUMAN
BioGRID, HPRD
15967462
details
MLRV_HUMAN
KPYM_HUMAN
BioGRID
25412762
details
MLRV_HUMAN
ROCK2_HUMAN
BioGRID
25412762
details
MLRV_HUMAN
PP12C_HUMAN
HPRD
11399775
details
MLRV_HUMAN
MRCKA_HUMAN
HPRD
9418861
details
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