Entity Details

Primary name ERR1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP11474
EntryNameERR1_HUMAN
FullNameSteroid hormone receptor ERR1
TaxID9606
Evidenceevidence at protein level
Length423
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesESRRA

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001650 fibrillar center
GO:0003700 DNA-binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0004879 nuclear receptor activity
GO:0005496 steroid binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0007005 mitochondrion organization
GO:0008270 zinc ion binding
GO:0015630 microtubule cytoskeleton
GO:0019904 protein domain specific binding
GO:0043565 sequence-specific DNA binding
GO:0045171 intercellular bridge
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR024178 Estrogen receptor/oestrogen-related receptorFamilyFamily
IPR027289 Oestrogen-related receptorFamilyFamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00197 TroglitazoneDrugbanksmall molecule
DB00255 DiethylstilbestrolDrugbanksmall molecule
DB01645 GenisteinDrugbanksmall molecule
DB04468 AfimoxifeneDrugbanksmall molecule
DB06732 beta-NaphthoflavoneDrugbanksmall molecule
DB06833 1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINEDrugbanksmall molecule
DB07776 FlavoneDrugbanksmall molecule

Interactions

41 interactions

InteractorPartnerSourcesPublicationsLink
ERR1_HUMANPNRC2_HUMANHPRD, MINT11574675 details
ERR1_HUMANADHX_HUMANBioGRID, IntAct21988832 details
ERR1_HUMANFUS_HUMANBioGRID, IntAct21988832 details
ERR1_HUMANMP2K5_HUMANBioGRID, IntAct21988832 details
ERR1_HUMANNXF1_HUMANBioGRID, IntAct21988832 details
ERR1_HUMANPIAS4_HUMANBioGRID, IntAct18063693 21988832 details
ERR1_HUMANATX1_HUMANBioGRID, IntAct23275563 details
ERR1_HUMANREL_HUMANBioGRID, IntAct32296183 details
ERR1_HUMANFAM9A_HUMANBioGRID, IntAct32296183 details
ERR1_HUMANERR3_HUMANBioGRID, HPRD, IntAct15604093 17157980 17488637 18673300 32296183 details
ERR1_HUMANTNNI2_HUMANBioGRID, IntAct15604093 32296183 details
ERR1_HUMANPRGC1_HUMANBioGRID, HPRD, IntAct12181319 12522104 15337744 18063693 18441008 32296183 details
ERR1_HUMANRNF4_HUMANBioGRID, IntAct32296183 details
ERR1_HUMANHIF1A_HUMANBioGRID, DIP18509053 details
ERR1_HUMANNCOA1_HUMANBioGRID, HPRD, IntAct11165056 15337744 15604093 23975195 details
ERR1_HUMANNCOA3_HUMANBioGRID, HPRD10598588 15604093 details
ERR1_HUMANLYST_HUMANBioGRID, HPRD11984006 details
ERR1_HUMANNRIP1_HUMANBioGRID15604093 16439465 details
ERR1_HUMANSP1_HUMANBioGRID16439465 details
ERR1_HUMANKAT2B_HUMANBioGRID20484414 details
ERR1_HUMANSIR1_HUMANBioGRID20484414 details
ERR1_HUMANHDAC8_HUMANBioGRID20484414 details
ERR1_HUMANNR0B1_HUMANBioGRID, HPRD15604093 details
ERR1_HUMANDUT_HUMANBioGRID, HPRD15604093 details
ERR1_HUMANPROX1_HUMANBioGRID, HPRD15604093 details
ERR1_HUMANNR0B2_HUMANBioGRID, HPRD15604093 details
ERR1_HUMANMACF1_HUMANBioGRID15604093 details
ERR1_HUMANSMRD3_HUMANBioGRID14701856 details
ERR1_HUMANESR1_HUMANBioGRID, HPRD12522104 23403292 9058380 9395481 details
ERR1_HUMANEXOS6_HUMANBioGRID, HPRD15231747 details
ERR1_HUMANNSD1_HUMANBioGRID23975195 details
ERR1_HUMANPRS8_HUMANBioGRID15604093 details
ERR1_HUMANPPARG_HUMANBioGRID12522104 details
ERR1_HUMANRXRA_HUMANBioGRID12522104 details
ERR1_HUMANSUMO3_HUMANIntAct18063693 details
ERR1_HUMANPRKN_HUMANBioGRID21177257 details
ERR1_HUMANLYRIC_HUMANBioGRID28627585 details
ERR1_HUMANCHIP_HUMANBioGRID31907393 details
ERR1_HUMANTF2B_HUMANHPRD9058380 details
ERR1_HUMANERR1_HUMANHPRD16024613 details
ERR1_HUMANKPCD_HUMANHPRD16024613 details