Entity Details

Primary name FGF5_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP12034
EntryNameFGF5_HUMAN
FullNameFibroblast growth factor 5
TaxID9606
Evidenceevidence at protein level
Length268
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesFGF5

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0001934 positive regulation of protein phosphorylation
GO:0005104 fibroblast growth factor receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0007267 cell-cell signaling
GO:0007399 nervous system development
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008543 fibroblast growth factor receptor signaling pathway
GO:0009887 animal organ morphogenesis
GO:0010001 glial cell differentiation
GO:0010628 positive regulation of gene expression
GO:0023019 signal transduction involved in regulation of gene expression
GO:0030154 cell differentiation
GO:0030334 regulation of cell migration
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR002209 Fibroblast growth factor familyFamilyFamily
IPR008996 Cytokine IL1/FGFFamilyHomologous superfamily
IPR028240 Fibroblast growth factor 5FamilyFamily

Diseases

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Disease IDSourceNameDescription
190330 OMIMTrichomegaly (TCMGLY)A morphologic trait characterized by unusually long eyelashes and mild hypertrichosis of eyebrows. It can be observed in association with corneal irritation, cataracts, and hereditary spherocytosis. The disease is caused by variants affecting the gene represented in this entry.

Interactions

5 interactions