Entity Details

Primary name MYH7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP12883
EntryNameMYH7_HUMAN
FullNameMyosin-7
TaxID9606
Evidenceevidence at protein level
Length1935
SequenceStatuscomplete
DateCreated1989-10-01
DateModified2021-06-02

Ontological Relatives

GenesMYH7

GO terms

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GOName
GO:0000146 microfilament motor activity
GO:0001725 stress fiber
GO:0002026 regulation of the force of heart contraction
GO:0002027 regulation of heart rate
GO:0003009 skeletal muscle contraction
GO:0005516 calmodulin binding
GO:0005524 ATP binding
GO:0005859 muscle myosin complex
GO:0006936 muscle contraction
GO:0006941 striated muscle contraction
GO:0007512 adult heart development
GO:0014728 regulation of the force of skeletal muscle contraction
GO:0014883 transition between fast and slow fiber
GO:0014898 cardiac muscle hypertrophy in response to stress
GO:0016459 myosin complex
GO:0016887 ATP hydrolysis activity
GO:0030016 myofibril
GO:0030017 sarcomere
GO:0030018 Z disc
GO:0030049 muscle filament sliding
GO:0031449 regulation of slow-twitch skeletal muscle fiber contraction
GO:0032982 myosin filament
GO:0046034 ATP metabolic process
GO:0051015 actin filament binding
GO:0055010 ventricular cardiac muscle tissue morphogenesis
GO:0060048 cardiac muscle contraction

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR000048 IQ motif, EF-hand binding siteSiteBinding site
IPR001609 Myosin head, motor domainDomainDomain
IPR002928 Myosin tailDomainDomain
IPR004009 Myosin, N-terminal, SH3-likeDomainDomain
IPR008989 Myosin S1 fragment, N-terminalFamilyHomologous superfamily
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036961 Kinesin motor domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB08378 4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACIDDrugbanksmall molecule