Entity Details

Primary name AT1A3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP13637
EntryNameAT1A3_HUMAN
FullNameSodium/potassium-transporting ATPase subunit alpha-3
TaxID9606
Evidenceevidence at protein level
Length1013
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesATP1A3

GO terms

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GOName
GO:0001540 amyloid-beta binding
GO:0001917 photoreceptor inner segment
GO:0005391 P-type sodium:potassium-exchanging transporter activity
GO:0005524 ATP binding
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0005890 sodium:potassium-exchanging ATPase complex
GO:0006883 cellular sodium ion homeostasis
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030007 cellular potassium ion homeostasis
GO:0030424 axon
GO:0031090 organelle membrane
GO:0032809 neuronal cell body membrane
GO:0034220 ion transmembrane transport
GO:0036376 sodium ion export across plasma membrane
GO:0043025 neuronal cell body
GO:0045202 synapse
GO:0046872 metal ion binding
GO:0051087 chaperone binding
GO:0060075 regulation of resting membrane potential
GO:0060342 photoreceptor inner segment membrane
GO:0071383 cellular response to steroid hormone stimulus
GO:0086064 cell communication by electrical coupling involved in cardiac conduction
GO:0098984 neuron to neuron synapse
GO:0099520 ion antiporter activity involved in regulation of presynaptic membrane potential
GO:1902600 proton transmembrane transport
GO:1903416 response to glycoside
GO:1903561 extracellular vesicle
GO:1903779 regulation of cardiac conduction
GO:1904646 cellular response to amyloid-beta
GO:1990239 steroid hormone binding
GO:1990535 neuron projection maintenance
GO:1990573 potassium ion import across plasma membrane

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001757 P-type ATPaseFamilyFamily
IPR004014 Cation-transporting P-type ATPase, N-terminalDomainDomain
IPR005775 P-type ATPase subfamily IIC, subunit alphaFamilyFamily
IPR006068 Cation-transporting P-type ATPase, C-terminalDomainDomain
IPR008250 P-type ATPase, A domain superfamilyFamilyHomologous superfamily
IPR018303 P-type ATPase, phosphorylation sitePTMPTM
IPR023214 HAD superfamilyFamilyHomologous superfamily
IPR023298 P-type ATPase, transmembrane domain superfamilyFamilyHomologous superfamily
IPR023299 P-type ATPase, cytoplasmic domain NFamilyHomologous superfamily
IPR036412 HAD-like superfamilyFamilyHomologous superfamily
IPR044492 P-type ATPase, haloacid dehalogenase domainDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB01092 OuabainDrugbanksmall molecule
DB09479 Rubidium Rb-82Swissprotsmall molecule