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Entity Details
Primary name
K1C10_HUMAN
Entity type
UniProt
Source
Source Link
Details
Accession
P13645
EntryName
K1C10_HUMAN
FullName
Keratin, type I cytoskeletal 10
TaxID
9606
Evidence
evidence at protein level
Length
584
SequenceStatus
complete
DateCreated
1990-01-01
DateModified
2021-06-02
Ontological Relatives
Genes
KRT10
GO terms
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GO
Name
GO:0001533
cornified envelope
GO:0005615
extracellular space
GO:0005634
nucleus
GO:0005737
cytoplasm
GO:0005829
cytosol
GO:0005882
intermediate filament
GO:0009986
cell surface
GO:0016020
membrane
GO:0018149
peptide cross-linking
GO:0030216
keratinocyte differentiation
GO:0030280
structural constituent of skin epidermis
GO:0031424
keratinization
GO:0045684
positive regulation of epidermis development
GO:0046982
protein heterodimerization activity
GO:0051290
protein heterotetramerization
GO:0070062
extracellular exosome
GO:0070268
cornification
Subcellular Location
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Subcellular Location
Cell surface
Secreted
Domains
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Domain
Name
Category
Type
IPR002957
Keratin, type I
Family
Family
IPR018039
Intermediate filament protein, conserved site
Site
Conserved site
IPR039008
Intermediate filament, rod domain
Domain
Domain
Diseases
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Drugs
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Drug
Name
Source
Type
DB01593
Zinc
Drugbank
small molecule
DB09130
Copper
Drugbank
small molecule
DB14487
Zinc acetate
Drugbank
small molecule
Interactions
13 interactions
Interactor
Partner
Sources
Publications
Link
K1C10_HUMAN
K2C1_HUMAN
BioGRID, UniProt
22939629
26344197
27595935
details
K1C10_HUMAN
GLE1_HUMAN
BioGRID
14645504
details
K1C10_HUMAN
AKT1_HUMAN
BioGRID, HPRD
11585925
details
K1C10_HUMAN
ESR1_HUMAN
BioGRID
20348541
details
K1C10_HUMAN
SHPS1_HUMAN
BioGRID
19299420
details
K1C10_HUMAN
SNAPN_HUMAN
BioGRID
23414517
details
K1C10_HUMAN
OGT1_HUMAN
BioGRID
32994395
details
K1C10_HUMAN
SRC_HUMAN
BioGRID, MINT
17868192
details
K1C10_HUMAN
KPCZ_HUMAN
BioGRID, HPRD
11585925
details
K1C10_HUMAN
GAN_HUMAN
BioGRID
26460568
details
K1C10_HUMAN
TRAF6_HUMAN
BioGRID
27507811
details
K1C10_HUMAN
MDM2_HUMAN
BioGRID
31626786
details
K1C10_HUMAN
EVPL_HUMAN
HPRD
8999895
details
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