Entity Details

Primary name ONCM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP13725
EntryNameONCM_HUMAN
FullNameOncostatin-M
TaxID9606
Evidenceevidence at protein level
Length252
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesOSM

GO terms

Show/Hide Table
GOName
GO:0002675 positive regulation of acute inflammatory response
GO:0005125 cytokine activity
GO:0005147 oncostatin-M receptor binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006955 immune response
GO:0007275 multicellular organism development
GO:0008083 growth factor activity
GO:0008284 positive regulation of cell population proliferation
GO:0008285 negative regulation of cell population proliferation
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling
GO:0019221 cytokine-mediated signaling pathway
GO:0032740 positive regulation of interleukin-17 production
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0038165 oncostatin-M-mediated signaling pathway
GO:0040008 regulation of growth
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein
GO:0043410 positive regulation of MAPK cascade
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046888 negative regulation of hormone secretion
GO:0050729 positive regulation of inflammatory response
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0051781 positive regulation of cell division
GO:0051897 positive regulation of protein kinase B signaling
GO:1902036 regulation of hematopoietic stem cell differentiation

Subcellular Location

Show/Hide Table
Subcellular Location
Secreted

Domains

Show/Hide Table
DomainNameCategoryType
IPR001581 Leukemia inhibitory factor /oncostatinFamilyFamily
IPR009079 Four-helical cytokine-like, coreFamilyHomologous superfamily
IPR019827 Leukemia inhibitory factor /oncostatin, conserved siteSiteConserved site
IPR039578 Oncostatin-MFamilyFamily

Diseases

Show/Hide Table