Entity Details

Primary name CTRB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP17538
EntryNameCTRB1_HUMAN
FullNameChymotrypsinogen B
TaxID9606
Evidenceevidence at transcript level
Length263
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesCTRB1

GO terms

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GOName
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0006508 proteolysis
GO:0007586 digestion
GO:0009235 cobalamin metabolic process
GO:0022617 extracellular matrix disassembly

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001254 Serine proteases, trypsin domainDomainDomain
IPR001314 Peptidase S1A, chymotrypsin familyFamilyFamily
IPR009003 Peptidase S1, PA clanFamilyHomologous superfamily
IPR018114 Serine proteases, trypsin family, histidine active siteSiteActive site
IPR033116 Serine proteases, trypsin family, serine active siteSiteActive site
IPR043504 Peptidase S1, PA clan, chymotrypsin-like foldFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01662 Trans-O-Hydroxy-Alpha-Methyl CinnamateDrugbanksmall molecule
DB01704 2,4-Dihydroxy-Trans Cinnamic AcidDrugbanksmall molecule
DB01963 Phenylethane Boronic AcidDrugbanksmall molecule
DB03976 PhosphorylisopropaneDrugbanksmall molecule
DB06692 AprotininDrugbankbiotech
DB07380 1,1,1-TRIFLUORO-3-ACETAMIDO-4-PHENYL BUTAN-2-ONE(N-ACETYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE)Drugbanksmall molecule
DB07383 N-(1-BENZYL-3,3,3-TRIFLUORO-2,2-DIHYDROXY-PROPYL)-ACETAMIDEDrugbanksmall molecule
DB07668 alpha-Methyl-2-hydroxy-4-diethylaminocinnamic acidDrugbanksmall molecule
DB07749 2-ACETYLAMINO-4-METHYL-PENTANOIC ACID (1-FORMYL-2-PHENYL-ETHYL)-AMIDEDrugbanksmall molecule
DB07899 (2S) N-acetyl-L-alanyl-aL-phenylalanyl-chloroethylketoneDrugbanksmall molecule
DB08119 1,1,1-TRIFLUORO-3-((N-ACETYL)-L-LEUCYLAMIDO)-4-PHENYL-BUTAN-2-ONE(N-ACETYL-L-LEUCYL-L-PHENYLALANYL TRIFLUOROMETHYL KETONE)Drugbanksmall molecule
DB08374 PhenylalanylmethylchlorideDrugbanksmall molecule
DB08565 L-1-naphthyl-2-acetamido-ethane boronic acidDrugbanksmall molecule
DB08566 D-1-naphthyl-2-acetamido-ethane boronic acidDrugbanksmall molecule
DB08692 D-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acidDrugbanksmall molecule
DB08693 L-1-(4-chlorophenyl)-2-(acetamido)ethane boronic acidDrugbanksmall molecule