Entity Details

Primary name PYRG1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP17812
EntryNamePYRG1_HUMAN
FullNameCTP synthase 1
TaxID9606
Evidenceevidence at protein level
Length591
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesCTPS1

GO terms

Show/Hide Table
GOName
GO:0003883 CTP synthase activity
GO:0005524 ATP binding
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006139 nucleobase-containing compound metabolic process
GO:0006241 CTP biosynthetic process
GO:0006541 glutamine metabolic process
GO:0015949 nucleobase-containing small molecule interconversion
GO:0016020 membrane
GO:0019856 pyrimidine nucleobase biosynthetic process
GO:0042098 T cell proliferation
GO:0042100 B cell proliferation
GO:0042493 response to drug
GO:0042802 identical protein binding
GO:0044210 'de novo' CTP biosynthetic process
GO:0097268 cytoophidium

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR004468 CTP synthaseFamilyFamily
IPR017456 CTP synthase, N-terminalDomainDomain
IPR017926 Glutamine amidotransferaseDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR029062 Class I glutamine amidotransferase-likeFamilyHomologous superfamily
IPR033828 CTP synthase GATase domainDomainDomain

Diseases

Show/Hide Table

Drugs

Show/Hide Table
DrugNameSourceType
DB00130 L-GlutamineDrugbanksmall molecule