Entity Details

Primary name GPDA_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP21695
EntryNameGPDA_HUMAN
FullNameGlycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
TaxID9606
Evidenceevidence at protein level
Length349
SequenceStatuscomplete
DateCreated1991-05-01
DateModified2021-06-02

Ontological Relatives

GenesGPD1

GO terms

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GOName
GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity
GO:0004368 glycerol-3-phosphate dehydrogenase (quinone) activity
GO:0005829 cytosol
GO:0006072 glycerol-3-phosphate metabolic process
GO:0006094 gluconeogenesis
GO:0006116 NADH oxidation
GO:0006127 glycerophosphate shuttle
GO:0006654 phosphatidic acid biosynthetic process
GO:0009331 glycerol-3-phosphate dehydrogenase complex
GO:0042803 protein homodimerization activity
GO:0045821 positive regulation of glycolytic process
GO:0046168 glycerol-3-phosphate catabolic process
GO:0051287 NAD binding
GO:0070062 extracellular exosome
GO:0071320 cellular response to cAMP
GO:0071356 cellular response to tumor necrosis factor

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminalDomainDomain
IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependentFamilyFamily
IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamilyFamilyHomologous superfamily
IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminalDomainDomain
IPR013328 6-phosphogluconate dehydrogenase, domain 2FamilyHomologous superfamily
IPR017751 Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryoticFamilyFamily
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00157 NADHDrugbanksmall molecule
DB00331 MetforminDrugbanksmall molecule