Entity Details

Primary name NK3R_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP29371
EntryNameNK3R_HUMAN
FullNameNeuromedin-K receptor
TaxID9606
Evidenceevidence at protein level
Length465
SequenceStatuscomplete
DateCreated1992-12-01
DateModified2021-06-02

Ontological Relatives

GenesTACR3

GO terms

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GOName
GO:0004995 tachykinin receptor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007217 tachykinin receptor signaling pathway
GO:0007568 aging
GO:0010460 positive regulation of heart rate
GO:0032355 response to estradiol
GO:0032590 dendrite membrane
GO:0032809 neuronal cell body membrane
GO:0042053 regulation of dopamine metabolic process
GO:0042220 response to cocaine
GO:0042538 hyperosmotic salinity response
GO:0043278 response to morphine
GO:0045777 positive regulation of blood pressure
GO:0060259 regulation of feeding behavior
GO:0070474 positive regulation of uterine smooth muscle contraction
GO:0097225 sperm midpiece
GO:1902093 positive regulation of flagellated sperm motility

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000276 G protein-coupled receptor, rhodopsin-likeFamilyFamily
IPR001013 Neurokinin NK3 receptorFamilyFamily
IPR001681 Neurokinin receptorFamilyFamily
IPR017452 GPCR, rhodopsin-like, 7TMDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB04872 OsanetantDrugbanksmall molecule
DB06429 TalnetantDrugbanksmall molecule
DB11692 PavinetantDrugbanksmall molecule

Interactions

3 interactions