Entity Details

Primary name GRIK1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP39086
EntryNameGRIK1_HUMAN
FullNameGlutamate receptor ionotropic, kainate 1
TaxID9606
Evidenceevidence at protein level
Length918
SequenceStatuscomplete
DateCreated1995-02-01
DateModified2021-06-02

Ontological Relatives

GenesGRIK1

GO terms

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GOName
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0007215 glutamate receptor signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007399 nervous system development
GO:0007417 central nervous system development
GO:0008066 glutamate receptor activity
GO:0015276 ligand-gated ion channel activity
GO:0015277 kainate selective glutamate receptor activity
GO:0035249 synaptic transmission, glutamatergic
GO:0038023 signaling receptor activity
GO:0045211 postsynaptic membrane
GO:0050804 modulation of chemical synaptic transmission
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane

Domains

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DomainNameCategoryType
IPR001320 Ionotropic glutamate receptorDomainDomain
IPR001508 Ionotropic glutamate receptor, metazoaFamilyFamily
IPR001828 Receptor, ligand binding regionDomainDomain
IPR019594 Ionotropic glutamate receptor, L-glutamate and glycine-binding domainDomainDomain
IPR028082 Periplasmic binding protein-like IFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00142 Glutamic acidDrugbanksmall molecule
DB00237 ButabarbitalDrugbanksmall molecule
DB00273 TopiramateDrugbanksmall molecule
DB06354 TezampanelDrugbanksmall molecule