Entity Details

Primary name EAA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP43003
EntryNameEAA1_HUMAN
FullNameExcitatory amino acid transporter 1
TaxID9606
Evidenceevidence at protein level
Length542
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesSLC1A3

GO terms

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GOName
GO:0001504 neurotransmitter uptake
GO:0005313 L-glutamate transmembrane transporter activity
GO:0005314 high-affinity glutamate transmembrane transporter activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006811 ion transport
GO:0006836 neurotransmitter transport
GO:0007268 chemical synaptic transmission
GO:0009925 basal plasma membrane
GO:0015501 glutamate:sodium symporter activity
GO:0015813 L-glutamate transmembrane transport
GO:0016020 membrane
GO:0031410 cytoplasmic vesicle
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0045202 synapse
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0051938 L-glutamate import
GO:0070633 transepithelial transport
GO:0070779 D-aspartate import across plasma membrane
GO:0071805 potassium ion transmembrane transport
GO:0098712 L-glutamate import across plasma membrane
GO:0098796 membrane protein complex
GO:0140009 L-aspartate import across plasma membrane
GO:0150104 transport across blood-brain barrier
GO:1902476 chloride transmembrane transport

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001991 Sodium:dicarboxylate symporterFamilyFamily
IPR018107 Sodium:dicarboxylate symporter, conserved siteSiteConserved site
IPR036458 Sodium:dicarboxylate symporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00142 Glutamic acidDrugbanksmall molecule
DB08868 FingolimodDrugbanksmall molecule