Entity Details

Primary name EAA2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP43004
EntryNameEAA2_HUMAN
FullNameExcitatory amino acid transporter 2
TaxID9606
Evidenceevidence at protein level
Length574
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesSLC1A2

GO terms

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GOName
GO:0005313 L-glutamate transmembrane transporter activity
GO:0005314 high-affinity glutamate transmembrane transporter activity
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006811 ion transport
GO:0006836 neurotransmitter transport
GO:0007268 chemical synaptic transmission
GO:0009986 cell surface
GO:0015501 glutamate:sodium symporter activity
GO:0015813 L-glutamate transmembrane transport
GO:0016020 membrane
GO:0044297 cell body
GO:0045121 membrane raft
GO:0046872 metal ion binding
GO:0070207 protein homotrimerization
GO:0070633 transepithelial transport
GO:0070778 L-aspartate transmembrane transport
GO:0070779 D-aspartate import across plasma membrane
GO:0097449 astrocyte projection
GO:0098712 L-glutamate import across plasma membrane
GO:0098796 membrane protein complex
GO:0099056 integral component of presynaptic membrane
GO:0150104 transport across blood-brain barrier

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR001991 Sodium:dicarboxylate symporterFamilyFamily
IPR018107 Sodium:dicarboxylate symporter, conserved siteSiteConserved site
IPR036458 Sodium:dicarboxylate symporter superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB00142 Glutamic acidDrugbanksmall molecule
DB08868 FingolimodDrugbanksmall molecule

Interactions

6 interactions