Entity Details

Primary name NPC2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionP61916
EntryNameNPC2_HUMAN
FullNameNPC intracellular cholesterol transporter 2
TaxID9606
Evidenceevidence at protein level
Length151
SequenceStatuscomplete
DateCreated2004-06-07
DateModified2021-06-02

Ontological Relatives

GenesNPC2

GO terms

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GOName
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0005783 endoplasmic reticulum
GO:0008203 cholesterol metabolic process
GO:0009615 response to virus
GO:0015485 cholesterol binding
GO:0015914 phospholipid transport
GO:0015918 sterol transport
GO:0019747 regulation of isoprenoid metabolic process
GO:0019899 enzyme binding
GO:0030301 cholesterol transport
GO:0032366 intracellular sterol transport
GO:0032367 intracellular cholesterol transport
GO:0032934 sterol binding
GO:0033344 cholesterol efflux
GO:0034383 low-density lipoprotein particle clearance
GO:0035578 azurophil granule lumen
GO:0042632 cholesterol homeostasis
GO:0043202 lysosomal lumen
GO:0043312 neutrophil degranulation
GO:0046836 glycolipid transport
GO:0070062 extracellular exosome
GO:0120020 cholesterol transfer activity

Subcellular Location

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Subcellular Location
Endoplasmic reticulum
Lysosome
Secreted

Domains

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DomainNameCategoryType
IPR003172 MD-2-related lipid-recognition domainDomainDomain
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR033916 Npc2 like, ML domainDomainDomain
IPR039670 Sterol transport protein NPC2-likeFamilyFamily

Diseases

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