Entity Details

Primary name CO4A3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ01955
EntryNameCO4A3_HUMAN
FullNameCollagen alpha-3(IV) chain
TaxID9606
Evidenceevidence at protein level
Length1670
SequenceStatuscomplete
DateCreated1996-10-01
DateModified2021-06-02

Ontological Relatives

GenesCOL4A3

GO terms

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GOName
GO:0005178 integrin binding
GO:0005198 structural molecule activity
GO:0005201 extracellular matrix structural constituent
GO:0005576 extracellular region
GO:0005587 collagen type IV trimer
GO:0005604 basement membrane
GO:0005615 extracellular space
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007155 cell adhesion
GO:0007166 cell surface receptor signaling pathway
GO:0007605 sensory perception of sound
GO:0008015 blood circulation
GO:0008191 metalloendopeptidase inhibitor activity
GO:0008285 negative regulation of cell population proliferation
GO:0009749 response to glucose
GO:0016525 negative regulation of angiogenesis
GO:0030020 extracellular matrix structural constituent conferring tensile strength
GO:0030198 extracellular matrix organization
GO:0030199 collagen fibril organization
GO:0031012 extracellular matrix
GO:0032836 glomerular basement membrane development
GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway
GO:0043231 intracellular membrane-bounded organelle
GO:0062023 collagen-containing extracellular matrix
GO:0072577 endothelial cell apoptotic process
GO:1905563 negative regulation of vascular endothelial cell proliferation

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001442 Collagen IV, non-collagenousDomainDomain
IPR008160 Collagen triple helix repeatRepeatRepeat
IPR016187 C-type lectin foldFamilyHomologous superfamily
IPR036954 Collagen IV, non-collagenous domain superfamilyFamilyHomologous superfamily

Diseases

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