Entity Details

Primary name ADCY5
Entity type gene
Source Source Link

Details

PrimaryID111
RefseqGeneNG_033882
SymbolADCY5
Nameadenylate cyclase 5
Chromosome3
Location3q21.1
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1997-11-18
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsADCY5_HUMAN

GO terms

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GOName
GO:0001973 G protein-coupled adenosine receptor signaling pathway
GO:0002862 negative regulation of inflammatory response to antigenic stimulus
GO:0003091 renal water homeostasis
GO:0004016 adenylate cyclase activity
GO:0005524 ATP binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005929 cilium
GO:0006171 cAMP biosynthetic process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0007190 activation of adenylate cyclase activity
GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007626 locomotory behavior
GO:0008179 adenylate cyclase binding
GO:0016021 integral component of membrane
GO:0034199 activation of protein kinase A activity
GO:0035556 intracellular signal transduction
GO:0045111 intermediate filament cytoskeleton
GO:0046872 metal ion binding
GO:0050885 neuromuscular process controlling balance
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0071377 cellular response to glucagon stimulus
GO:0097110 scaffold protein binding
GO:1904322 cellular response to forskolin

Diseases

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Disease IDSourceNameDescription
606703 OMIMDyskinesia, familial, with facial myokymia (FDFM)A disorder characterized by predominantly perioral and periorbital myokymia, and face, neck and upper limb dystonic/choreic movements. Initially paroxysmal and worsened by stress, the dyskinetic episodes become nearly constant by the end of the third decade of life, but in some individuals, they may diminish in frequency and severity at older ages. The disease is caused by variants affecting the gene represented in this entry.

Interactions

11 interactions