Entity Details

Primary name CTSZ
Entity type gene
Source Source Link

Details

PrimaryID1522
RefseqGeneNG_023300
SymbolCTSZ
Namecathepsin Z
Chromosome20
Location20q13.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-27
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsCATZ_HUMAN

GO terms

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GOName
GO:0002003 angiotensin maturation
GO:0004180 carboxypeptidase activity
GO:0004197 cysteine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005886 plasma membrane
GO:0006508 proteolysis
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0008234 cysteine-type peptidase activity
GO:0010757 negative regulation of plasminogen activation
GO:0030134 COPII-coated ER to Golgi transport vesicle
GO:0031410 cytoplasmic vesicle
GO:0032091 negative regulation of protein binding
GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane
GO:0035580 specific granule lumen
GO:0043312 neutrophil degranulation
GO:0048208 COPII vesicle coating
GO:0051603 proteolysis involved in cellular protein catabolic process
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0099738 cell cortex region
GO:1901214 regulation of neuron death
GO:1904813 ficolin-1-rich granule lumen

Diseases

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Interactions

26 interactions

InteractorPartnerSourcesPublicationsLink
CTSZKRTAP5-9BioGRID, IntAct, MINT21516116 25416956 31515488 32296183 details
CTSZPLSCR1BioGRID, IntAct25416956 details
CTSZMTUS2BioGRID, IntAct25416956 31515488 details
CTSZKRT40BioGRID, IntAct25416956 details
CTSZNOTCH2NLABioGRID, IntAct25416956 31515488 32296183 details
CTSZMID2BioGRID, IntAct25416956 32296183 details
CTSZFHL5BioGRID, IntAct32296183 details
CTSZTNS2BioGRID, IntAct32296183 details
CTSZKRT35BioGRID, IntAct32296183 details
CTSZBACH2BioGRID, IntAct32296183 details
CTSZKRTAP2-3BioGRID, IntAct32296183 details
CTSZKRTAP2-4BioGRID, IntAct32296183 details
CTSZKRTAP10-10BioGRID, IntAct32296183 details
CTSZBANPBioGRID, IntAct32296183 details
CTSZCYSRT1BioGRID, IntAct32296183 details
CTSZKRTAP3-3BioGRID, IntAct32296183 details
CTSZKRTAP1-1BioGRID, IntAct32296183 details
CTSZHSF2BPBioGRID, IntAct32296183 details
CTSZKRTAP10-1BioGRID32296183 details
CTSZPLK2BioGRID, IntAct26496610 details
CTSZPLECBioGRID, IntAct30021884 details
CTSZFBXO6BioGRID22268729 details
CTSZEFTUD2BioGRID28515276 details
CTSZAAR2BioGRID28515276 details
CTSZPIH1D1BioGRID28515276 details
CTSZHNRNPH1BioGRID26760575 details