Entity Details

Primary name ENPP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13822
EntryNameENPP2_HUMAN
FullNameEctonucleotide pyrophosphatase/phosphodiesterase family member 2
TaxID9606
Evidenceevidence at protein level
Length863
SequenceStatuscomplete
DateCreated2002-09-19
DateModified2021-06-02

Ontological Relatives

GenesENPP2

GO terms

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GOName
GO:0003676 nucleic acid binding
GO:0004528 phosphodiesterase I activity
GO:0004551 nucleotide diphosphatase activity
GO:0004622 lysophospholipase activity
GO:0005044 scavenger receptor activity
GO:0005509 calcium ion binding
GO:0005615 extracellular space
GO:0005886 plasma membrane
GO:0006935 chemotaxis
GO:0006955 immune response
GO:0008134 transcription factor binding
GO:0008270 zinc ion binding
GO:0009395 phospholipid catabolic process
GO:0010634 positive regulation of epithelial cell migration
GO:0016787 hydrolase activity
GO:0030149 sphingolipid catabolic process
GO:0030247 polysaccharide binding
GO:0030334 regulation of cell migration
GO:0034638 phosphatidylcholine catabolic process
GO:0045765 regulation of angiogenesis
GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity
GO:0048870 cell motility
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:2000394 positive regulation of lamellipodium morphogenesis

Subcellular Location

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Subcellular Location
Secreted

Domains

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DomainNameCategoryType
IPR001212 Somatomedin B domainDomainDomain
IPR001604 DNA/RNA non-specific endonucleaseDomainDomain
IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferaseFamilyFamily
IPR017850 Alkaline-phosphatase-like, core domain superfamilyFamilyHomologous superfamily
IPR020436 Somatomedin B, chordataDomainDomain
IPR020821 Extracellular Endonuclease, subunit ADomainDomain
IPR029881 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2FamilyFamily
IPR036024 Somatomedin B-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
ENPP2_HUMANHSPB1_HUMANBioGRID, IntAct25277244 details
ENPP2_HUMANITB4_HUMANBioGRID21696367 details
ENPP2_HUMANLPAR1_HUMANBioGRID21696367 details