Entity Details

Primary name ELANE
Entity type gene
Source Source Link

Details

PrimaryID1991
RefseqGeneNG_009627
SymbolELANE
Nameelastase, neutrophil expressed
Chromosome19
Location19p13.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1994-01-04
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsELNE_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001878 response to yeast
GO:0002020 protease binding
GO:0002438 acute inflammatory response to antigenic stimulus
GO:0002523 leukocyte migration involved in inflammatory response
GO:0002812 biosynthetic process of antibacterial peptides active against Gram-negative bacteria
GO:0003714 transcription corepressor activity
GO:0004175 endopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0006508 proteolysis
GO:0006874 cellular calcium ion homeostasis
GO:0006909 phagocytosis
GO:0008201 heparin binding
GO:0008233 peptidase activity
GO:0009411 response to UV
GO:0009986 cell surface
GO:0017053 transcription repressor complex
GO:0019730 antimicrobial humoral response
GO:0019955 cytokine binding
GO:0022617 extracellular matrix disassembly
GO:0030141 secretory granule
GO:0030163 protein catabolic process
GO:0032496 response to lipopolysaccharide
GO:0032682 negative regulation of chemokine production
GO:0032717 negative regulation of interleukin-8 production
GO:0032757 positive regulation of interleukin-8 production
GO:0035578 azurophil granule lumen
GO:0035580 specific granule lumen
GO:0042742 defense response to bacterium
GO:0043312 neutrophil degranulation
GO:0043406 positive regulation of MAP kinase activity
GO:0045335 phagocytic vesicle
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0050728 negative regulation of inflammatory response
GO:0050778 positive regulation of immune response
GO:0050922 negative regulation of chemotaxis
GO:0062023 collagen-containing extracellular matrix
GO:0070062 extracellular exosome
GO:0070945 neutrophil-mediated killing of gram-negative bacterium
GO:0070947 neutrophil-mediated killing of fungus
GO:1903238 positive regulation of leukocyte tethering or rolling

Diseases

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