Entity Details

Primary name FZD2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14332
EntryNameFZD2_HUMAN
FullNameFrizzled-2
TaxID9606
Evidenceevidence at protein level
Length565
SequenceStatuscomplete
DateCreated2001-12-05
DateModified2021-06-02

Ontological Relatives

GenesFZD2

GO terms

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GOName
GO:0003149 membranous septum morphogenesis
GO:0003150 muscular septum morphogenesis
GO:0003151 outflow tract morphogenesis
GO:0004930 G protein-coupled receptor activity
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0007223 Wnt signaling pathway, calcium modulating pathway
GO:0007608 sensory perception of smell
GO:0016021 integral component of membrane
GO:0016055 Wnt signaling pathway
GO:0017147 Wnt-protein binding
GO:0030165 PDZ domain binding
GO:0030182 neuron differentiation
GO:0030669 clathrin-coated endocytic vesicle membrane
GO:0030855 epithelial cell differentiation
GO:0042813 Wnt-activated receptor activity
GO:0045893 positive regulation of transcription, DNA-templated
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0060022 hard palate development
GO:0060070 canonical Wnt signaling pathway
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0060119 inner ear receptor cell development
GO:0090103 cochlea morphogenesis
GO:0090179 planar cell polarity pathway involved in neural tube closure
GO:1904886 beta-catenin destruction complex disassembly

Subcellular Location

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Subcellular Location
Cell membrane
Membrane

Domains

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DomainNameCategoryType
IPR000539 Frizzled/Smoothened, transmembrane domainDomainDomain
IPR015526 Frizzled/secreted frizzled-related proteinFamilyFamily
IPR017981 GPCR, family 2-likeDomainDomain
IPR020067 Frizzled domainDomainDomain
IPR026550 Frizzled-1/2FamilyFamily
IPR036790 Frizzled cysteine-rich domain superfamilyFamilyHomologous superfamily
IPR041778 Frizzled 2, cysteine-rich domainDomainDomain

Diseases

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