Entity Details

Primary name TBX21
Entity type gene
Source Source Link

Details

PrimaryID30009
RefseqGeneNG_012166
SymbolTBX21
NameT-box transcription factor 21
Chromosome17
Location17q21.32
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate2000-02-29
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsTBX21_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001708 cell fate specification
GO:0001947 heart looping
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007275 multicellular organism development
GO:0009615 response to virus
GO:0030217 T cell differentiation
GO:0032703 negative regulation of interleukin-2 production
GO:0043025 neuronal cell body
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043565 sequence-specific DNA binding
GO:0045580 regulation of T cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048304 positive regulation of isotype switching to IgG isotypes
GO:0071310 cellular response to organic substance
GO:0072676 lymphocyte migration
GO:1990837 sequence-specific double-stranded DNA binding
GO:2000320 negative regulation of T-helper 17 cell differentiation
GO:2000329 negative regulation of T-helper 17 cell lineage commitment
GO:2000552 negative regulation of T-helper 2 cell cytokine production

Diseases

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Interactions

9 interactions

InteractorPartnerSourcesPublicationsLink
TBX21EXOC5BioGRID, IntAct21988832 details
TBX21HOXC11BioGRID, IntAct20211142 details
TBX21ZNF490BioGRID, IntAct20211142 details
TBX21EP300BioGRID, DIP17075044 details
TBX21GATA3BioGRID, DIP17075044 details
TBX21SP1BioGRID, DIP17075044 details
TBX21CREBBPBioGRID, DIP17075044 details
TBX21USP10BioGRID24845384 details
TBX21UBCBioGRID24845384 details