Entity Details

Primary name SF01_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15637
EntryNameSF01_HUMAN
FullNameSplicing factor 1
TaxID9606
Evidenceevidence at protein level
Length639
SequenceStatuscomplete
DateCreated2003-11-07
DateModified2021-06-02

Ontological Relatives

GenesSF1

GO terms

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GOName
GO:0000245 spliceosomal complex assembly
GO:0000389 mRNA 3'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0003714 transcription corepressor activity
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005840 ribosome
GO:0008270 zinc ion binding
GO:0042802 identical protein binding
GO:0045131 pre-mRNA branch point binding
GO:0048024 regulation of mRNA splicing, via spliceosome

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR001878 Zinc finger, CCHC-typeDomainDomain
IPR004087 K Homology domainDomainDomain
IPR004088 K Homology domain, type 1DomainDomain
IPR031150 BBP/SF1 familyFamilyFamily
IPR032570 Splicing factor 1, helix-hairpin domainDomainDomain
IPR036612 K Homology domain, type 1 superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB11638 ArtenimolDrugbanksmall molecule

Interactions

114 interactions

InteractorPartnerSourcesPublicationsLink
SF01_HUMANCD2B2_HUMANMINT15105431 details
SF01_HUMANPLS1_HUMANBioGRID, HPRD, IntAct16189514 details
SF01_HUMANTRI23_HUMANBioGRID, HPRD, IntAct16189514 details
SF01_HUMANDDX17_HUMANBioGRID, IntAct, MINT16189514 22365833 26420826 details
SF01_HUMANWWP2_HUMANBioGRID, HPRD, IntAct16189514 details
SF01_HUMANRBPMS_HUMANBioGRID, HPRD, IntAct16189514 26420826 details
SF01_HUMANU2AF2_HUMANBioGRID, DIP, HPRD, IntAct, MINT12718882 16189514 22365833 23273425 26420826 26641092 32296183 9150140 9512519 details
SF01_HUMANTITIN_HUMANBioGRID, IntAct23414517 details
SF01_HUMANSF3A1_HUMANBioGRID, IntAct, MINT22365833 26420826 details
SF01_HUMANSF3B4_HUMANBioGRID, MINT22365833 details
SF01_HUMANSPF45_HUMANBioGRID, DIP, IntAct, MINT17589525 22365833 26420826 32296183 details
SF01_HUMANRBM10_HUMANBioGRID, MINT22365833 details
SF01_HUMANSF01_HUMANBioGRID, IntAct, MINT22365833 26420826 details
SF01_HUMANILF3_HUMANBioGRID, MINT22365833 details
SF01_HUMANU5S1_HUMANBioGRID, MINT22365833 22939629 28515276 details
SF01_HUMANSPF27_HUMANBioGRID, MINT22365833 details
SF01_HUMANWDR83_HUMANBioGRID, MINT22365833 details
SF01_HUMANRBM7_HUMANBioGRID, MINT22365833 details
SF01_HUMANHNRPK_HUMANBioGRID, MINT22365833 details
SF01_HUMANHNRL1_HUMANBioGRID, MINT22365833 details
SF01_HUMANRBM4_HUMANBioGRID, MINT22365833 details
SF01_HUMANMEP50_HUMANBioGRID, MINT22365833 details
SF01_HUMANHNRPF_HUMANBioGRID, MINT22365833 details
SF01_HUMANHNRH1_HUMANBioGRID, MINT22365833 details
SF01_HUMANHNRH2_HUMANBioGRID, MINT22365833 26344197 details
SF01_HUMANATX1_HUMANBioGRID, IntAct, UniProt23275563 25959826 32814053 details
SF01_HUMANCIAO1_HUMANBioGRID, IntAct23891004 25416956 details
SF01_HUMANPSA3_HUMANBioGRID, IntAct25416956 30009671 details
SF01_HUMANMKRN3_HUMANBioGRID, IntAct25416956 details
SF01_HUMANKR261_HUMANBioGRID, IntAct25416956 details
SF01_HUMANTRI69_HUMANBioGRID, IntAct25416956 details
SF01_HUMANF168A_HUMANBioGRID, IntAct25416956 31515488 details
SF01_HUMANSF3B1_HUMANBioGRID, IntAct26420826 31110137 details
SF01_HUMANCHERP_HUMANIntAct26420826 details
SF01_HUMANPUF60_HUMANBioGRID, IntAct26420826 32296183 details
SF01_HUMANPR40A_HUMANBioGRID, HPRD, IntAct15456888 16055720 26420826 details
SF01_HUMANSFSWA_HUMANIntAct26420826 details
SF01_HUMANCDC42_HUMANBioGRID, IntAct26496610 31478661 details
SF01_HUMANSC23A_HUMANBioGRID, IntAct32296183 details
SF01_HUMANUBL5_HUMANBioGRID, IntAct32296183 details
SF01_HUMANTXN4B_HUMANBioGRID, IntAct32296183 details
SF01_HUMANTNPO2_HUMANBioGRID, IntAct32296183 details
SF01_HUMANNCK2_HUMANBioGRID, IntAct32296183 details
SF01_HUMANEWS_HUMANBioGRID, HPRD9660765 details
SF01_HUMANFUS_HUMANBioGRID, HPRD25192599 9660765 details
SF01_HUMANRBP56_HUMANBioGRID, HPRD9660765 details
SF01_HUMANTCRG1_HUMANBioGRID, HPRD11604498 15456888 16055720 details
SF01_HUMANZN461_HUMANBioGRID16595694 details
SF01_HUMANNFKB1_HUMANBioGRID12917325 details
SF01_HUMANHDAC5_HUMANBioGRID12917325 details
SF01_HUMANITCH_HUMANBioGRID16055720 details
SF01_HUMANWBP4_HUMANBioGRID16055720 details
SF01_HUMANAPBB1_HUMANBioGRID16055720 details
SF01_HUMANGAS7_HUMANBioGRID16055720 details
SF01_HUMANOSTF1_HUMANBioGRID32296183 details
SF01_HUMANOGT1_HUMANBioGRID32994395 details
SF01_HUMANSF3A2_HUMANBioGRID, IntAct, MINT17332742 26420826 details
SF01_HUMANHNRDL_HUMANIntAct26420826 details
SF01_HUMANIMA3_HUMANIntAct26420826 details
SF01_HUMANCE104_HUMANIntAct26420826 details
SF01_HUMANIMA7_HUMANIntAct26420826 details
SF01_HUMANRBMS1_HUMANIntAct26420826 details
SF01_HUMANTISD_HUMANIntAct26420826 details
SF01_HUMANIMA1_HUMANIntAct26420826 details
SF01_HUMANTISB_HUMANIntAct26420826 details
SF01_HUMANIMA5_HUMANIntAct26420826 details
SF01_HUMANANM2_HUMANBioGRID, IntAct26186194 26420826 details
SF01_HUMANDDB1_HUMANIntAct26420826 details
SF01_HUMANTET5C_HUMANIntAct26420826 details
SF01_HUMANFUBP3_HUMANBioGRID, IntAct26420826 29395067 details
SF01_HUMANUHMK1_HUMANIntAct26420826 details
SF01_HUMANKHDC4_HUMANIntAct26420826 details
SF01_HUMANPKCB1_HUMANIntAct26420826 details
SF01_HUMANROAA_HUMANIntAct26420826 details
SF01_HUMANIMA4_HUMANIntAct26420826 details
SF01_HUMANIMA6_HUMANIntAct26420826 details
SF01_HUMANKHDR3_HUMANIntAct26420826 details
SF01_HUMANKDM4B_HUMANIntAct26420826 details
SF01_HUMANNU155_HUMANIntAct26420826 details
SF01_HUMANABL1_HUMANIntAct26420826 details
SF01_HUMANDDX5_HUMANIntAct26420826 details
SF01_HUMANTPR_HUMANIntAct26420826 details
SF01_HUMANSCP2_HUMANIntAct26420826 details
SF01_HUMANCO8A1_HUMANIntAct26420826 details
SF01_HUMANABL2_HUMANIntAct26420826 details
SF01_HUMANVAV2_HUMANIntAct26420826 details
SF01_HUMANRBM5_HUMANIntAct26420826 details
SF01_HUMANTIAR_HUMANIntAct26420826 details
SF01_HUMANCLH1_HUMANIntAct26420826 details
SF01_HUMANKHDR1_HUMANIntAct26420826 details
SF01_HUMANRBMS2_HUMANIntAct26420826 details
SF01_HUMANPHF19_HUMANIntAct26420826 details
SF01_HUMANMSI2H_HUMANIntAct26420826 details
SF01_HUMANCENPI_HUMANIntAct26420826 details
SF01_HUMANTGS1_HUMANIntAct26420826 details
SF01_HUMANMD2L2_HUMANIntAct26420826 details
SF01_HUMANP3C2B_HUMANIntAct26420826 details
SF01_HUMANTIA1_HUMANIntAct26420826 details
SF01_HUMANHNRPD_HUMANIntAct26420826 details
SF01_HUMANMBTD1_HUMANIntAct26420826 details
SF01_HUMANDAZP1_HUMANIntAct26420826 details
SF01_HUMANPLAL2_HUMANIntAct26420826 details
SF01_HUMANTTP_HUMANIntAct26420826 details
SF01_HUMANNCOR2_HUMANBioGRID16002533 details
SF01_HUMANPML_HUMANBioGRID21360626 details
SF01_HUMANPRGC1_HUMANBioGRID20133449 details
SF01_HUMANHDAC4_HUMANBioGRID12917325 27684187 details
SF01_HUMANMET22_HUMANBioGRID23349634 details
SF01_HUMANITA4_HUMANBioGRID22623428 details
SF01_HUMANNCOA1_HUMANBioGRID16002533 details
SF01_HUMANNXF1_HUMANBioGRID29395067 details
SF01_HUMANDAZL_HUMANBioGRID29395067 details
SF01_HUMANKGP1_HUMANHPRD10449420 details
SF01_HUMANBCL2_HUMANHPRD8668206 details