Entity Details

Primary name MYB
Entity type gene
Source Source Link

Details

PrimaryID4602
RefseqGeneNG_012330
SymbolMYB
NameMYB proto-oncogene, transcription factor
Chromosome6
Location6q23.3
TaxID9606
Statuslive
SourceGenomegenomic
SourceOriginnatural
CreationDate1998-08-20
ModificationDate2021-06-11

Ontological Relatives

UniProt IDsMYB_HUMAN

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000278 mitotic cell cycle
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001666 response to hypoxia
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006338 chromatin remodeling
GO:0006355 regulation of transcription, DNA-templated
GO:0016363 nuclear matrix
GO:0032967 positive regulation of collagen biosynthetic process
GO:0043525 positive regulation of neuron apoptotic process
GO:0045624 positive regulation of T-helper cell differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0051571 positive regulation of histone H3-K4 methylation
GO:0051574 positive regulation of histone H3-K9 methylation
GO:0060252 positive regulation of glial cell proliferation
GO:0070301 cellular response to hydrogen peroxide
GO:0071300 cellular response to retinoic acid
GO:0071636 positive regulation of transforming growth factor beta production
GO:1901533 negative regulation of hematopoietic progenitor cell differentiation
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:1904899 positive regulation of hepatic stellate cell proliferation
GO:2000491 positive regulation of hepatic stellate cell activation
GO:2000845 positive regulation of testosterone secretion

Diseases

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Interactions

90 interactions

InteractorPartnerSourcesPublicationsLink
MYBNLKBioGRID, HPRD, IntAct15082531 15308626 16055500 details
MYBHIPK2BioGRID, HPRD, IntAct15082531 16055500 details
MYBERC2BioGRID, IntAct20195357 details
MYBNCOR1BioGRID, IntAct14761981 20195357 details
MYBUPF2BioGRID, IntAct20195357 details
MYBSUMO1BioGRID, I2D20802522 details
MYBSUMO2BioGRID, I2D20802522 details
MYBPMLBioGRID, HPRD, I2D15194430 20802522 details
MYBPIAS1BioGRID, Molecular Connections21338522 27032383 details
MYBCCND3BioGRID, IntAct21988832 details
MYBMYOZ2BioGRID, IntAct21988832 details
MYBPPM1KBioGRID, IntAct21988832 details
MYBPAIP1BioGRID, IntAct32296183 details
MYBCREBBPBioGRID, DIP, HPRD11073948 12196545 14761981 16055500 16799563 23980173 details
MYBHLFBioGRID, IntAct20211142 details
MYBSP100BioGRID, IntAct20211142 details
MYBSMARCA2BioGRID10619021 details
MYBCEBPEBioGRID, HPRD10233885 details
MYBMAFBioGRID, HPRD9566892 details
MYBSND1BioGRID, HPRD8756344 9809063 details
MYBFBXW7BioGRID, HPRD18765672 21092141 details
MYBZMYND11BioGRID11244510 details
MYBEP300BioGRID, HPRD10656693 11585920 15691758 20364308 25740244 29954426 details
MYBTRIM28BioGRID14761981 details
MYBSKIBioGRID14761981 details
MYBSIN3ABioGRID14761981 details
MYBUBE2IBioGRID, HPRD11779867 22910413 27150054 details
MYBCHD3BioGRID17344210 details
MYBRPL4BioGRID20604807 details
MYBRBX1BioGRID18765672 details
MYBKAT2ABioGRID10656693 details
MYBH3-4BioGRID29954426 details
MYBH2AC4BioGRID29954426 details
MYBH2BC3BioGRID29954426 details
MYBH3C1BioGRID29954426 details
MYBH4C1BioGRID29954426 details
MYBTTF2HPRD12927788 details
MYBZFHX3HPRD10318867 details
MYBCNOT9HPRD15209511 details
MYBCLTCMINT18548008 details
MYBLIN9MINT18548008 details
MYBCOX7BIntAct20195357 details
MYBSDC2IntAct20195357 details
MYBZFC3H1IntAct20195357 details
MYBPTMSIntAct20195357 details
MYBKMT2EIntAct20195357 details
MYBSETD1AIntAct20195357 details
MYBNCAM2IntAct20195357 details
MYBBEX3IntAct20195357 details
MYBADAM22IntAct20195357 details
MYBKIF2AIntAct20195357 details
MYBFBXL5IntAct20195357 details
MYBPCDH17IntAct20195357 details
MYBTAL1DIP25394790 details
MYBNCLBioGRID, HPRD10660576 details
MYBCEBPBBioGRID, HPRD11792321 details
MYBPAX5BioGRID, HPRD11781241 details
MYBKMT2ABioGRID20093773 details
MYBWDR5BioGRID20093773 details
MYBRBBP5BioGRID20093773 details
MYBASH2LBioGRID20093773 details
MYBMEN1BioGRID20093773 details
MYBPARP1BioGRID18945670 details
MYBKAT2BBioGRID20364308 details
MYBLEF1BioGRID21795403 details
MYBKAT5BioGRID22110127 details
MYBGATA3BioGRID22039304 details
MYBSTAT5ABioGRID19036881 details
MYBTRAF6BioGRID18093978 27150054 details
MYBFBXW5BioGRID, HPRD18765672 22910413 details
MYBDDB1BioGRID22910413 details
MYBCUL4ABioGRID22910413 details
MYBHSPA8BioGRID23333597 details
MYBBMI1BioGRID32453568 details
MYBMAPK1HPRD8960373 details
MYBMYBBP1AHPRD8302594 9447996 details
MYBCSNK2A1HPRD11313925 details
MYBFBXW2HPRD18765672 details
MYBSKP2HPRD18765672 details
MYBBTRCHPRD18765672 details
MYBMAPK11IntAct14676314 details
MYBFLNAMINT18548008 details
MYBSPTAN1MINT18548008 details
MYBCLTAMINT18548008 details
MYBDCAF15BioGRID31452512 details
MYBMYCI2D20802522 details
MYBADAIntAct30076175 details
MYBVIRMABioGRID29507755 details
MYBAPEX1BioGRID28986522 details
MYBUPF1BioGRID31732746 details